Reaction profile

The FDA adverse-event record for active urine sediment

132 FDA adverse-event reports reference active urine sediment (VeDDRA 2699). See the species, breeds, and drugs most associated with it below.

132
reports citing this reaction
20.5%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
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132
Total Reports
27
Deaths
20.5%
Death Rate

Species Most Affected

Dog 107
Cat 23
Horse 2

Breeds Most Affected

Domestic Shorthair 15
Retriever - Labrador 14
Crossbred Canine/dog 7
Shih Tzu 5
Maltese 5
Beagle 5
Chihuahua 4
Retriever - Golden 4
Dog (other) 4
Siberian Husky 4

Associated Drugs

Trilostane 34
Carprofen 18
Bedinvetmab 17
Gabapentin 11
Bexagliflozin 10
Cefovecin Sodium 7
Moxidectin 7
Grapiprant 7
Butorphanol 7
Propofol 7
Oclacitinib Maleate 6
Pyrantel Pamoate;Sarolaner 6
Selamectin 5
Deracoxib 4
Firocoxib 4
Maropitant Citrate 4
Enrofloxacin 4
Prednisone 4
Amoxicillin 4
Pimobendan 4

Active urine sediment Reaction Insights

132 reports name Active urine sediment; 27 recorded a death outcome (20.5% of reported events, not a population-level mortality rate). VeDDRA code: 2699.

By species: Dog (107 reports), Cat (23 reports), Horse (2 reports). By breed: Domestic Shorthair (15), Retriever - Labrador (14), Crossbred Canine/dog (7).

Most co-reported drugs: Trilostane (34 reports), Carprofen (18 reports), Bedinvetmab (17 reports), Gabapentin (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.