Reaction profile

The FDA adverse-event record for active urine sediment

147 FDA adverse-event reports reference active urine sediment (VeDDRA 2699). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1198 of 2,481
by report volume (all reactions)
147
reports citing this reaction
19.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Active urine sediment has 147 reports now versus 143 in that prior snapshot: 4 more (2.8%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Active urine sediment changes

FDA AER · VeDDRA plate

Code 2699 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 147 reports
  • DEATH-ELEV 19.0%
  • MID-PACK #1198/2481
  • PHOTO-FINISH Myelopathy NOS
  • SPECIES-DOG Dog · 119
  • DRUG-LEAD Trilostane · 40
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Myelopathy NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Active urine sediment

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Active urine sediment · this…147Myelopathy NOS · near147Osteosarcoma · near147PR-PANCREAS, LESION(S) · near147Pruritic rash · near147Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Active urine sediment

What the FDA AER plate says about Active urine sediment

Signature read: 28 death-coded reports is the most distinctive absolute-outcome stamp on Active urine sediment. Report volume sits in the middle third of the reaction corpus. 28 of 147 reports were death-coded (19.0% of named reports, not a population mortality rate). Nearest volume peer: Myelopathy NOS (±0 reports). Lead species Dog (119). Lead co-reported drug Trilostane (40).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 119
Cat 26
Horse 2

Breeds Most Affected

Retriever - Labrador 16
Domestic Shorthair 15
Crossbred Canine/dog 9
Shih Tzu 5
Dog (other) 5
Boxer (German Boxer) 5
Beagle 5
Maltese 5
Chihuahua 4
Retriever - Golden 4

Associated Drugs

Trilostane 40
Carprofen 22
Bedinvetmab 19
Gabapentin 14
Oclacitinib Maleate 11
Bexagliflozin 11
Cefovecin Sodium 7
Moxidectin 7
Grapiprant 7
Pyrantel Pamoate;Sarolaner 7
Butorphanol 7
Propofol 7
Maropitant Citrate 5
Prednisone 5
Selamectin 5
Fluralaner 13.64% 12-Week Chew 5
Pimobendan 5
Deracoxib 4
Firocoxib 4
Enrofloxacin 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Active urine sediment, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (147 here).

Similar death-coded share

Nearest other reactions by death-coded share (19.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Active urine sediment (#1198 of 2,481 by report volume); death-coded 19.0%. PlainBreed reaction plate · death-coded report count stamp 28 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →