Active urine sediment

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VeDDRA Code: 2699

132 adverse event reports referencing this reaction

132
Total Reports
27
Deaths
2050.0%
Death Rate

Species Most Affected

Dog 107
Cat 23
Horse 2

Breeds Most Affected

Domestic Shorthair 15
Retriever - Labrador 14
Crossbred Canine/dog 7
Shih Tzu 5
Maltese 5
Beagle 5
Chihuahua 4
Retriever - Golden 4
Dog (other) 4
Siberian Husky 4

Associated Drugs

Trilostane 34
Carprofen 18
Bedinvetmab 17
Gabapentin 11
Bexagliflozin 10
Cefovecin Sodium 7
Moxidectin 7
Grapiprant 7
Butorphanol 7
Propofol 7
Oclacitinib Maleate 6
Pyrantel Pamoate;Sarolaner 6
Selamectin 5
Deracoxib 4
Firocoxib 4
Maropitant Citrate 4
Enrofloxacin 4
Prednisone 4
Amoxicillin 4
Pimobendan 4

Data Summary

Metric Value
Total reports referencing reaction 132
Reports with fatal outcome 27
Case-fatality rate (reported events) 2050.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2699.

Active urine sediment Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 132 adverse event reports that reference Active urine sediment as a reaction term, including 27 reports with a death outcome — a 2050.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2699, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Active urine sediment appears most frequently in reports for Dog (107 reports), Cat (23 reports), Horse (2 reports) — with Dog dominating at 107 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (15), Retriever - Labrador (14), Crossbred Canine/dog (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Active urine sediment are Trilostane (34 reports), Carprofen (18 reports), Bedinvetmab (17 reports), Gabapentin (11 reports), with Trilostane appearing alongside this reaction in 34 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial