Reaction profile

The FDA adverse-event record for tracheal and laryngeal disorder nos

131 FDA adverse-event reports reference tracheal and laryngeal disorder nos (VeDDRA 1849). See the species, breeds, and drugs most associated with it below.

131
reports citing this reaction
32.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
131
Total Reports
43
Deaths
32.8%
Death Rate

Species Most Affected

Dog 105
Cat 13
Cattle 6
Human 4
Llama 1
Rabbit 1
Horse 1

Breeds Most Affected

Terrier - Yorkshire 9
Spitz - German Pomeranian 8
Domestic Shorthair 6
Unknown 5
Chihuahua 5
Retriever - Labrador 5
Retriever - Golden 5
Terrier - Boston 5
Bulldog 4
Domestic Longhair 4

Associated Drugs

Milbemycin Oxime + Spinosad 17
Spinosad 15
Trilostane 9
Fluralaner Chew Tablets 9
Oclacitinib Maleate 8
Bedinvetmab 8
Maropitant Citrate 7
Carprofen 6
Dexmedetomidine Hydrochloride 5
Fluralaner 13.64% 12-Week Chew 5
Ivermectin + Pyrantel As Pamoate Salt 4
Butorphanol 4
Isoflurane 4
Milbemycin Oxime 4
Cefovecin 4
Grapiprant 4
Gabapentin 4
Galliprant 4
Ivermectin + Pyrantel Pamoate 3
Ceftiofur Crystalline Free Acid 3

Tracheal and laryngeal disorder NOS Reaction Insights

131 reports name Tracheal and laryngeal disorder NOS; 43 recorded a death outcome (32.8% of reported events, not a population-level mortality rate). VeDDRA code: 1849.

By species: Dog (105 reports), Cat (13 reports), Cattle (6 reports). By breed: Terrier - Yorkshire (9), Spitz - German Pomeranian (8), Domestic Shorthair (6).

Most co-reported drugs: Milbemycin Oxime + Spinosad (17 reports), Spinosad (15 reports), Trilostane (9 reports), Fluralaner Chew Tablets (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.