Reaction profile

The FDA adverse-event record for increased intracranial pressure

10 FDA adverse-event reports reference increased intracranial pressure (VeDDRA 634). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
80.0%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
10
Total Reports
8
Deaths
80.0%
Death Rate

Species Most Affected

Dog 9
Cat 1

Breeds Most Affected

Chihuahua 3
Terrier - Yorkshire 2
Shepherd Dog - Australian 1
Crossbred Canine/dog 1
Domestic Shorthair 1
Sheepdog - Shetland 1
Shih Tzu 1

Associated Drugs

Bedinvetmab 3
Carprofen 2
Buprenorphine 2
Fluid Therapy 2
Maropitant 2
Anti-Il31 Mab Mcs Lot #1283563 2
Meloxicam 2
Zyrtec 2
Diphenhydramine 2
Cinnamon 2
Tumeric 2
Cbd 2
Chinese Herbs 2
Gabapentin 2
Moxidectin 1
Ivermectin 1
Diazepam 1
Phenobarbital 1
Dexamethasone Sodium Phosphate 1
Ivermectin + Pyrantel As Pamoate Salt 1

Increased intracranial pressure Reaction Insights

10 reports name Increased intracranial pressure; 8 recorded a death outcome (80.0% of reported events, not a population-level mortality rate). VeDDRA code: 634.

By species: Dog (9 reports), Cat (1 reports). By breed: Chihuahua (3), Terrier - Yorkshire (2), Shepherd Dog - Australian (1).

Most co-reported drugs: Bedinvetmab (3 reports), Carprofen (2 reports), Buprenorphine (2 reports), Fluid Therapy (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.