Sexual disorder NOS (see 'Reproductive' for named sexual disorders)

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VeDDRA Code: 138

66 adverse event reports referencing this reaction

66
Total Reports
13
Deaths
1970.0%
Death Rate

Species Most Affected

Cattle 59
Dog 6
Cat 1

Breeds Most Affected

Mixed (Cattle) 24
Holstein-Friesian also known as Holstein 15
Crossbred Bovine/Cattle 8
Cattle (other) 4
Cattle (unknown) 3
Aberdeen Angus 3
Terrier - Jack Russell 1
Chihuahua 1
Dog (other) 1
Dog (unknown) 1

Associated Drugs

Trenbolone Acetate;Estradiol Benzoate 28
Estradiol Benzoate; Trenbolone Acetate 11
Melengestrol Acetate 10
Monensin Sodium 7
Trenbolone Acet/Estrad Sr Imp 7
Trenbolone Acet/Estradiol Impl 5
Estradiol 3
Progesterone; Estradiol Benzoate 3
Doramectin 3
Ractopamine Hydrochloride 2
Trilostane 2
Fenbendazol Suspension 2
Ibr/Brsv/P13/Bvd T1, T2(Us) Lv 2
Spinosad 1
Ivermectin 1
Pimobendan 1
Lufenuron + Milbemycin Oxime 1
Milbemycin / Spinosad 1
Cyclosporine A 1
Sometribove 1

Data Summary

Metric Value
Total reports referencing reaction 66
Reports with fatal outcome 13
Case-fatality rate (reported events) 1970.0%
Species observed 3
Breeds observed 15
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 138.

Sexual disorder NOS (see 'Reproductive' for named sexual disorders) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 66 adverse event reports that reference Sexual disorder NOS (see 'Reproductive' for named sexual disorders) as a reaction term, including 13 reports with a death outcome — a 1970.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 138, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Sexual disorder NOS (see 'Reproductive' for named sexual disorders) appears most frequently in reports for Cattle (59 reports), Dog (6 reports), Cat (1 reports) — with Cattle dominating at 59 entries. Within those species, the breeds most often named alongside this reaction are Mixed (Cattle) (24), Holstein-Friesian also known as Holstein (15), Crossbred Bovine/Cattle (8). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Sexual disorder NOS (see 'Reproductive' for named sexual disorders) are Trenbolone Acetate;Estradiol Benzoate (28 reports), Estradiol Benzoate; Trenbolone Acetate (11 reports), Melengestrol Acetate (10 reports), Monensin Sodium (7 reports), with Trenbolone Acetate;Estradiol Benzoate appearing alongside this reaction in 28 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial