Reaction profile

The FDA adverse-event record for sexual disorder nos (see 'reproductive' for named sexual disorders)

66 FDA adverse-event reports reference sexual disorder nos (see 'reproductive' for named sexual disorders) (VeDDRA 138). See the species, breeds, and drugs most associated with it below.

66
reports citing this reaction
19.7%
death-coded share
Cattle
most-affected species
Trenbolone Acetate;Estradiol Benzoate
most-associated drug
Verify with FDA CVM →
66
Total Reports
13
Deaths
19.7%
Death Rate

Species Most Affected

Cattle 59
Dog 6
Cat 1

Breeds Most Affected

Mixed (Cattle) 24
Holstein-Friesian also known as Holstein 15
Crossbred Bovine/Cattle 8
Cattle (other) 4
Cattle (unknown) 3
Aberdeen Angus 3
Terrier - Jack Russell 1
Chihuahua 1
Dog (other) 1
Dog (unknown) 1

Associated Drugs

Trenbolone Acetate;Estradiol Benzoate 28
Estradiol Benzoate; Trenbolone Acetate 11
Melengestrol Acetate 10
Monensin Sodium 7
Trenbolone Acet/Estrad Sr Imp 7
Trenbolone Acet/Estradiol Impl 5
Estradiol 3
Progesterone; Estradiol Benzoate 3
Doramectin 3
Ractopamine Hydrochloride 2
Trilostane 2
Fenbendazol Suspension 2
Ibr/Brsv/P13/Bvd T1, T2(Us) Lv 2
Spinosad 1
Ivermectin 1
Pimobendan 1
Lufenuron + Milbemycin Oxime 1
Milbemycin / Spinosad 1
Cyclosporine A 1
Sometribove 1

Sexual disorder NOS (see 'Reproductive' for named sexual disorders) Reaction Insights

66 reports name Sexual disorder NOS (see 'Reproductive' for named sexual disorders); 13 recorded a death outcome (19.7% of reported events, not a population-level mortality rate). VeDDRA code: 138.

By species: Cattle (59 reports), Dog (6 reports), Cat (1 reports). By breed: Mixed (Cattle) (24), Holstein-Friesian also known as Holstein (15), Crossbred Bovine/Cattle (8).

Most co-reported drugs: Trenbolone Acetate;Estradiol Benzoate (28 reports), Estradiol Benzoate; Trenbolone Acetate (11 reports), Melengestrol Acetate (10 reports), Monensin Sodium (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.