Reaction profile

The FDA adverse-event record for pr-adrenal(s), lesion(s)

Name: PR-ADRENAL(S), LESION(S) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

57 FDA reports name pr-adrenal(s), lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99588). Plate stamps and neighbourhood peers follow.

#1677 of 2,481
by report volume (all reactions): 57
reports citing this reaction: 100.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-ADRENAL(S), LESION(S) has 57 reports now versus 57 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-ADRENAL(S), LESION(S) changes

FDA AER · VeDDRA plate

Code 99588 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-LOW 57 reports
DEATH-HOT 100.0%
MID-PACK #1677/2481
PHOTO-FINISH Atrial fibrillation
SPECIES-DOG Dog · 44
DRUG-LEAD Moxidectin · 6
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Atrial fibrillation (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-ADRENAL, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around PR-ADRENAL(S), LESION(S)

PR-ADRENAL(S), LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-ADRENAL(S), LESION(S)'s 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 57 named reports in the openFDA extract. Death-coded share is upper-third: 57 of 57 reports (100.0% of named reports). Nearest volume peer: Atrial fibrillation (±0 reports). Lead species Dog (44). Lead co-reported drug Moxidectin (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 44

Cat 10

Horse 3

Breeds Most Affected

Collie - Border 6

Schnauzer (unspecified) 3

Domestic (unspecified) 3

Dachshund (unspecified) 3

Retriever - Golden 3

Domestic Shorthair 3

Crossbred Canine/dog 2

Pug 2

Beagle 2

Chihuahua 2

Associated Drugs

Moxidectin 6

Carprofen 6

Trilostane 6

Oclacitinib Maleate 5

Afoxolaner 4

Milbemycin Oxime + Spinosad 3

Maropitant Citrate 3

Meloxicam 2

Dexmedetomidine Hydrochloride 2

Robenacoxib 2

Imidacloprid + Moxidectin 2

Cefovecin 2

Ivermectin + Pyrantel As Pamoate Salt 2

Grapiprant 2

Ketamine Hydrochloride 1

Tiletamine, Zolazepam 1

Selamectin 1

Cefovecin Sodium 1

Water, Sodium Chloride, Potassium Chloride, Sodium Lactate, Calcium Chloride 1

Maropitant 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for PR-ADRENAL(S), LESION(S), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (57 here).

Atrial fibrillation 57 Epistaxis (unilateral) 57 Eyelid lump 57 Lack of efficacy (bacteria) - Mannheimia haemolytica 57

Similar death-coded share

Nearest other reactions by death-coded share (100.0% here), distinct from the volume row.

IGA Animal mortality greater than expected 100.0% NT - fibrinous (broncho) pneumonia/fibrinous pleuropneumonia 100.0% PR-LUNG(S), EDEMA 100.0% Found dead 99.8%

What to do with this reaction

Compare PR-ADRENAL, LESION's report profile against similar reactions nationwide. See similar reactions
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-ADRENAL(S), LESION(S) (#1677 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →