Reaction profile

The FDA adverse-event record for allergic pruritus

375 FDA reports name allergic pruritus, a high-volume reaction in the CVM extract (VeDDRA 2076). Plate stamps and neighbourhood peers follow.

#767 of 2,481
by report volume (all reactions)
375
reports citing this reaction
0.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Allergic pruritus has 375 reports now versus 372 in that prior snapshot: 3 more (0.8%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Allergic pruritus changes

FDA AER · VeDDRA plate

Code 2076 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 375 reports
  • DEATH-RARE 0.8%
  • MID-PACK #767/2481
  • PHOTO-FINISH Hyperchloraemia
  • SPECIES-DOG Dog · 351
  • DRUG-LEAD Moxidectin · 118
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hyperchloraemia (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Allergic pruritus

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal test result · near377Renal insufficiency · near376Allergic pruritus · this rea…375Hyperchloraemia · near375Monocytopenia · near374Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Allergic pruritus

Allergic pruritus: low death-coded share in the FDA AER plate

Signature read: Allergic pruritus's 0.8% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 375 named reports in the openFDA extract. Death-coded share is lower-third: 3 of 375 reports (0.8% of named reports). Nearest volume peer: Hyperchloraemia (±0 reports). Lead species Dog (351). Lead co-reported drug Moxidectin (118).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 351
Cat 11
Horse 6
Human 5
Cattle 2

Breeds Most Affected

Retriever - Labrador 44
Chihuahua 18
Retriever - Golden 15
Shih Tzu 14
Terrier - Bull - American Pit 14
Crossbred Canine/dog 13
Dachshund (unspecified) 12
Shepherd Dog - German 12
Boxer (German Boxer) 10
Domestic Shorthair 9

Associated Drugs

Moxidectin 118
Cyclosporine A 104
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 18
Rabies Virus, 15
Milbemycin Oxime + Spinosad 11
Oclacitinib Maleate 11
Anti-Il31 Mab Mcs Lot #1283563 11
Maropitant Citrate 11
Fluralaner Chew Tablets 10
Afoxolaner 136 Mg Chewable Tablets 9
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 9
Diphenhydramine 8
Prednisone 8
Afoxolaner 8
Cephalexin 7
Milbemycin Oxime + Praziquantel 7
Cyclosporine 6
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 6
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 6
Hydroxyzine 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Allergic pruritus, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (375 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Allergic pruritus (#767 of 2,481 by report volume); death-coded 0.8%. PlainBreed reaction plate · death-coded share stamp 0.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →