Allergic pruritus

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VeDDRA Code: 2076

368 adverse event reports referencing this reaction

368
Total Reports
3
Deaths
80.0%
Death Rate

Species Most Affected

Dog 345
Cat 11
Horse 5
Human 5
Cattle 2

Breeds Most Affected

Retriever - Labrador 42
Chihuahua 18
Retriever - Golden 15
Terrier - Bull - American Pit 14
Shih Tzu 13
Dachshund (unspecified) 12
Crossbred Canine/dog 12
Shepherd Dog - German 12
Boxer (German Boxer) 10
Domestic Shorthair 9

Associated Drugs

Moxidectin 114
Cyclosporine A 104
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 17
Rabies Virus, 15
Milbemycin Oxime + Spinosad 11
Maropitant Citrate 11
Oclacitinib Maleate 10
Fluralaner Chew Tablets 10
Anti-Il31 Mab Mcs Lot #1283563 10
Afoxolaner 136 Mg Chewable Tablets 9
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 9
Prednisone 8
Afoxolaner 8
Diphenhydramine 7
Milbemycin Oxime + Praziquantel 7
Cephalexin 6
Cyclosporine 6
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 6
Hydroxyzine 5
Dexamethasone 5

Data Summary

Metric Value
Total reports referencing reaction 368
Reports with fatal outcome 3
Case-fatality rate (reported events) 80.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2076.

Allergic pruritus Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 368 adverse event reports that reference Allergic pruritus as a reaction term, including 3 reports with a death outcome — a 80.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2076, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Allergic pruritus appears most frequently in reports for Dog (345 reports), Cat (11 reports), Horse (5 reports) — with Dog dominating at 345 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (42), Chihuahua (18), Retriever - Golden (15). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Allergic pruritus are Moxidectin (114 reports), Cyclosporine A (104 reports), Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str (17 reports), Rabies Virus, (15 reports), with Moxidectin appearing alongside this reaction in 114 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial