Reaction profile

The FDA adverse-event record for pr-bladder, lesion(s)

48 FDA adverse-event reports reference pr-bladder, lesion(s) (VeDDRA 99590). See the species, breeds, and drugs most associated with it below.

48
reports citing this reaction
87.5%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
48
Total Reports
42
Deaths
87.5%
Death Rate

Species Most Affected

Dog 31
Cat 15
Rat 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 9
Retriever - Labrador 6
Crossbred Canine/dog 3
Domestic (unspecified) 3
Beagle 2
Retriever - Golden 2
Sheepdog - Shetland 2
Terrier - West Highland White 2
Shepherd Dog - German 1
Dog (unknown) 1

Associated Drugs

Carprofen 7
Maropitant Citrate 6
Cefovecin 5
Famotidine 5
Oclacitinib Maleate 5
Cefovecin Sodium 4
Meloxicam 3
Maropitant 3
Robenacoxib 3
Enrofloxacin 3
Cefazolin 3
Buprenorphine 3
Milbemycin Oxime + Spinosad 2
Food 2
Dexmedetomidine Hydrochloride 2
Sucralfate 2
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 2
Ketamine 2
Hetastarch 2
Spinosad 2

PR-BLADDER, LESION(S) Reaction Insights

48 reports name PR-BLADDER, LESION(S); 42 recorded a death outcome (87.5% of reported events, not a population-level mortality rate). VeDDRA code: 99590.

By species: Dog (31 reports), Cat (15 reports), Rat (1 reports). By breed: Domestic Shorthair (9), Retriever - Labrador (6), Crossbred Canine/dog (3).

Most co-reported drugs: Carprofen (7 reports), Maropitant Citrate (6 reports), Cefovecin (5 reports), Famotidine (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.