Reaction profile

The FDA adverse-event record for skin lesion nos

4,169 FDA adverse-event reports reference skin lesion nos (VeDDRA 966). See the species, breeds, and drugs most associated with it below.

4,169
reports citing this reaction
6.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
4,169
Total Reports
276
Deaths
6.6%
Death Rate

Species Most Affected

Dog 3,024
Cat 949
Human 98
Cattle 33
Horse 28
Fish 13
Pig 5
Turkey 3
Chicken 3
Goat 3

Breeds Most Affected

Domestic Shorthair 538
Retriever - Labrador 322
Crossbred Canine/dog 204
Shepherd Dog - German 131
Unknown 120
Terrier - Yorkshire 117
Chihuahua 112
Retriever - Golden 110
Dog (unknown) 108
Shih Tzu 105

Associated Drugs

Oclacitinib Maleate 394
Milbemycin Oxime + Spinosad 353
Frunevetmab 308
Imidacloprid + Moxidectin 295
Carprofen 278
Selamectin 243
Afoxolaner 225
Cefovecin 204
Spinosad 178
Prednisone 144
Trilostane 137
Cyclosporine 116
Maropitant Citrate 113
Cefovecin Sodium 99
Gabapentin 97
Bedinvetmab 97
Cyclosporine A 96
Moxidectin 94
Anti-Il31 Mab Mcs Lot #1283563 90
Fluralaner Chew Tablets 89

Skin lesion NOS Reaction Insights

4,169 reports name Skin lesion NOS; 276 recorded a death outcome (6.6% of reported events, not a population-level mortality rate). VeDDRA code: 966.

By species: Dog (3,024 reports), Cat (949 reports), Human (98 reports). By breed: Domestic Shorthair (538), Retriever - Labrador (322), Crossbred Canine/dog (204).

Most co-reported drugs: Oclacitinib Maleate (394 reports), Milbemycin Oxime + Spinosad (353 reports), Frunevetmab (308 reports), Imidacloprid + Moxidectin (295 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.