Reaction profile

The FDA adverse-event record for application site serous discharge

93 FDA adverse-event reports reference application site serous discharge (VeDDRA 34). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1427 of 2,481
by report volume (all reactions)
93
reports citing this reaction
1.1%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Application site serous discharge has 93 reports now versus 90 in that prior snapshot: 3 more (3.3%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Application site serous discharge changes

FDA AER · VeDDRA plate

Code 34 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 93 reports
  • DEATH-LOW 1.1%
  • MID-PACK #1427/2481
  • PHOTO-FINISH Anterior uveitis
  • SPECIES-CAT Cat · 58
  • DRUG-LEAD Imidacloprid + Mo… · 23
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anterior uveitis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Application site serous discharge

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Anterior uveitis · near93Application site sero… · thi…93Intention tremor · near93Iris disorder · near93Unable to focus · near93Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Application site serous discharge

Application site serous discharge: low death-coded share in the FDA AER plate

Signature read: Application site serous discharge's 1.1% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 1 of 93 reports (1.1% of named reports). Nearest volume peer: Anterior uveitis (±0 reports). Lead species Cat (58). Lead co-reported drug Imidacloprid + Moxidectin (23).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Imidacloprid + Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 58
Dog 23
Unknown 8
Horse 2
Cattle 1
Human 1

Breeds Most Affected

Domestic Shorthair 35
Unknown 9
Pit Bull 7
Siamese 5
Maine Coon 4
Domestic Longhair 4
Crossbred Canine/dog 2
Dog (unknown) 2
Sphynx 2
Corso Dog 2

Associated Drugs

Imidacloprid + Moxidectin 23
Selamectin 20
Carprofen 9
Device: Suture 9
Selamectin;Sarolaner 7
Flumethrin-Imidacloprid 6
Bupivacaine Lipsome Injectable Suspension 5
Propofol 5
Gabapentin 5
Rabies Vaccine 4
Emodepside + Praziquantel 4
Buprenorphine 4
Isoflurane 4
Diphenhydramine 3
Hydromorphone 3
Cefovecin Sodium 3
Fluralaner/Moxidectin Spot-On 3
Cefovecin 3
Butorphanol 3
Trazodone 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Application site serous discharge, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (93 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Application site serous discharge (#1427 of 2,481 by report volume); death-coded 1.1%. PlainBreed reaction plate · death-coded share stamp 1.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →