Reaction profile

The FDA adverse-event record for pr-esophagus, lesion(s)

13 FDA adverse-event reports reference pr-esophagus, lesion(s) (VeDDRA 99611). See the species, breeds, and drugs most associated with it below.

13
reports citing this reaction
84.6%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
13
Total Reports
11
Deaths
84.6%
Death Rate

Species Most Affected

Dog 5
Cattle 3
Cat 3
Guinea Pig 1
Horse 1

Breeds Most Affected

Domestic (unspecified) 2
Unknown 1
Deutsche Dogge, Great Dane 1
Cattle (unknown) 1
Collie - Border 1
Charolais 1
Thoroughbred 1
Domestic Mediumhair 1
Siberian Husky 1
Jersey 1

Associated Drugs

Carprofen 2
Maropitant Citrate 2
Fluralaner Chew Tablets 2
Selamectin 1
Deracoxib 1
Albendazole 1
Famotidine 1
Anesthetic 1
Cephalexin 1
Amoxicillin, Clavulanate 1
Amoxicillin 1
Cefovecin Sodium 1
Ivermectin 1
Ceftiofur Crystalline Free Acid 1
Clindamycin Hydrochloride 1
Dexmedetomidine Hydrochloride 1
Cefovecin 1
Pegbovigrastim 1
Calcium 1
Ivermectin + Pyrantel As Pamoate Salt 1

PR-ESOPHAGUS, LESION(S) Reaction Insights

13 reports name PR-ESOPHAGUS, LESION(S); 11 recorded a death outcome (84.6% of reported events, not a population-level mortality rate). VeDDRA code: 99611.

By species: Dog (5 reports), Cattle (3 reports), Cat (3 reports). By breed: Domestic (unspecified) (2), Unknown (1), Deutsche Dogge, Great Dane (1).

Most co-reported drugs: Carprofen (2 reports), Maropitant Citrate (2 reports), Fluralaner Chew Tablets (2 reports), Selamectin (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.