Device breakage/fracture

Verify with FDA CVM →

VeDDRA Code: 93033

468 adverse event reports referencing this reaction

468
Total Reports
13
Deaths
280.0%
Death Rate

Species Most Affected

Unknown 249
Dog 135
Cat 56
Horse 16
Cattle 6
Pig 3
Rabbit 2
Human 1

Breeds Most Affected

Unknown 252
Dog (unknown) 105
Cat (unknown) 54
Horse (unknown) 16
Cattle (unknown) 5
Maltese 4
Greyhound 4
Pig (unknown) 3
Terrier - Yorkshire 3
Shepherd Dog - German 2

Associated Drugs

Device: Suture 137
Device: Surgical Instruments 82
Polyglactin 910 64
Device: Catheter 53
Velagliflozin Proline Monohydrate 40
Device: Syringe 25
Meloxicam 20
Telmisartan 10
Ciclesonide 6
Pimobendan 6
Device: Fluid Administration 4
Device: Diagnostic 3
Eprinomectin 3
Hyaluronate Sodium 2
Device: Bandaging 2
Omeprazole 2
Sodium Hyaluronate 2
Device: Radiography 1
Device: Endotracheal Tube 1
Device: Skin Stapler/Staples 1

Data Summary

Metric Value
Total reports referencing reaction 468
Reports with fatal outcome 13
Case-fatality rate (reported events) 280.0%
Species observed 8
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 93033.

Device breakage/fracture Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 468 adverse event reports that reference Device breakage/fracture as a reaction term, including 13 reports with a death outcome — a 280.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 93033, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Device breakage/fracture appears most frequently in reports for Unknown (249 reports), Dog (135 reports), Cat (56 reports) — with Unknown dominating at 249 entries. Within those species, the breeds most often named alongside this reaction are Unknown (252), Dog (unknown) (105), Cat (unknown) (54). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Device breakage/fracture are Device: Suture (137 reports), Device: Surgical Instruments (82 reports), Polyglactin 910 (64 reports), Device: Catheter (53 reports), with Device: Suture appearing alongside this reaction in 137 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial