Reaction profile

The FDA adverse-event record for polydipsia

9,145 FDA adverse-event reports reference polydipsia (VeDDRA 543). See the species, breeds, and drugs most associated with it below.

9,145
reports citing this reaction
11.7%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
9,145
Total Reports
1,066
Deaths
11.7%
Death Rate

Species Most Affected

Dog 8,161
Cat 869
Horse 97
Cattle 7
Pig 2
Chicken 2
Cockatiel 2
Human 1
Monkey 1
Rabbit 1

Breeds Most Affected

Retriever - Labrador 973
Crossbred Canine/dog 675
Domestic Shorthair 477
Retriever - Golden 366
Shepherd Dog - German 321
Boxer (German Boxer) 274
Dog (unknown) 253
Chihuahua 205
Shih Tzu 198
Terrier - Yorkshire 181

Associated Drugs

Bedinvetmab 1,469
Trilostane 1,217
Carprofen 895
Oclacitinib Maleate 684
Prednisone 433
Gabapentin 386
Fluralaner Chew Tablets 364
Milbemycin Oxime + Spinosad 359
Maropitant Citrate 301
Afoxolaner 296
Pyrantel Pamoate;Sarolaner 239
Spinosad 237
Moxidectin 222
Meloxicam 212
Deracoxib 209
Desoxycorticosterone Pivalate 192
Grapiprant 183
Anti-Il31 Mab Mcs Lot #1283563 175
Cyclosporine 174
Bexagliflozin 163

Polydipsia Reaction Insights

9,145 reports name Polydipsia; 1,066 recorded a death outcome (11.7% of reported events, not a population-level mortality rate). VeDDRA code: 543.

By species: Dog (8,161 reports), Cat (869 reports), Horse (97 reports). By breed: Retriever - Labrador (973), Crossbred Canine/dog (675), Domestic Shorthair (477).

Most co-reported drugs: Bedinvetmab (1,469 reports), Trilostane (1,217 reports), Carprofen (895 reports), Oclacitinib Maleate (684 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.