Reaction profile

The FDA adverse-event record for increased mortality rate

243 FDA adverse-event reports reference increased mortality rate (VeDDRA 2092). See the species, breeds, and drugs most associated with it below.

243
reports citing this reaction
97.9%
death-coded share
Chicken
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
243
Total Reports
238
Deaths
97.9%
Death Rate

Species Most Affected

Chicken 89
Cattle 82
Turkey 44
Pig 15
Fish 6
Other Birds 5
Pigeon 1
Partridge 1

Breeds Most Affected

Chicken (unknown) 71
Cattle (other) 58
Turkey (unknown) 42
Chicken (other) 15
Pig (unknown) 13
Holstein-Friesian also known as Holstein 10
Mixed (Cattle) 9
Cattle (unknown) 3
Other Birds (other) 3
Fish (other) 3

Associated Drugs

Monensin Sodium 59
Ceftiofur Crystalline Free Acid 45
Tulathromycin 44
Narasin + Nicarbazin 40
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 32
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 31
Narasin 26
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 18
Avilamycin 12
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D; Bovine Viral D 11
Wet-Milled Fenbendaz Oral Susp 8
Mannheimia Haemolytica Type A1, Nl-1009, Capsular Antigen, Kb; Mannheimia Haemol 6
Doramectin; Phenol 6
Florfenicol Premix Pwd Aquacul 6
Bacitracin Methylene Disalicylate 5
Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost 4
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Infectious Bovine Rhin 4
Lasalocid Sodium 4
Trenbolone; Estradiol; Tylosin Tartrate 4
Enrofloxacin 4

Increased mortality rate Reaction Insights

243 reports name Increased mortality rate; 238 recorded a death outcome (97.9% of reported events, not a population-level mortality rate). VeDDRA code: 2092.

By species: Chicken (89 reports), Cattle (82 reports), Turkey (44 reports). By breed: Chicken (unknown) (71), Cattle (other) (58), Turkey (unknown) (42).

Most co-reported drugs: Monensin Sodium (59 reports), Ceftiofur Crystalline Free Acid (45 reports), Tulathromycin (44 reports), Narasin + Nicarbazin (40 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.