Drug dispensing error

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VeDDRA Code: 99822

253 adverse event reports referencing this reaction

253
Total Reports
21
Deaths
830.0%
Death Rate

Species Most Affected

Dog 188
Cat 30
Unknown 13
Cattle 9
Chicken 3
Human 3
Pig 2
Goat 1
Sheep 1
Turkey 1

Breeds Most Affected

Unknown 21
Terrier - Yorkshire 19
Chihuahua 16
Shih Tzu 13
Dog (unknown) 11
Domestic Shorthair 10
Domestic (unspecified) 9
Spaniel - King Charles Cavalier 7
Schnauzer (unspecified) 7
Maltese 6

Associated Drugs

Milbemycin Oxime + Spinosad 74
Spinosad 34
Trilostane 13
Monensin Sodium 13
Oclacitinib Maleate 13
Carprofen 12
Levothyroxine Sodium 12
Fluralaner 13.64% 12-Week Chew 12
Human Insulin 9
Clomipramine 7
Ivermectin 6
Fluralaner Chew Tablets 6
Imidacloprid + Moxidectin 5
Clomipramine Hydrochloride 5
Lufenuron + Milbemycin Oxime 5
Selamectin 4
Firocoxib 4
Ivermectin + Pyrantel 3
Gabapentin 3
Grapiprant 3

Data Summary

Metric Value
Total reports referencing reaction 253
Reports with fatal outcome 21
Case-fatality rate (reported events) 830.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99822.

Drug dispensing error Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 253 adverse event reports that reference Drug dispensing error as a reaction term, including 21 reports with a death outcome — a 830.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99822, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Drug dispensing error appears most frequently in reports for Dog (188 reports), Cat (30 reports), Unknown (13 reports) — with Dog dominating at 188 entries. Within those species, the breeds most often named alongside this reaction are Unknown (21), Terrier - Yorkshire (19), Chihuahua (16). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Drug dispensing error are Milbemycin Oxime + Spinosad (74 reports), Spinosad (34 reports), Trilostane (13 reports), Monensin Sodium (13 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 74 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial