Reaction profile

The FDA adverse-event record for depressed ocular reflex

73 FDA adverse-event reports reference depressed ocular reflex (VeDDRA 1098). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1548 of 2,481
by report volume (all reactions)
73
reports citing this reaction
30.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Depressed ocular reflex has 73 reports now versus 71 in that prior snapshot: 2 more (2.8%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Depressed ocular reflex changes

FDA AER · VeDDRA plate

Code 1098 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 73 reports
  • DEATH-HOT 30.1%
  • MID-PACK #1548/2481
  • PHOTO-FINISH MAGNESIUM HIGH, BLOOD
  • SPECIES-DOG Dog · 54
  • DRUG-LEAD Prednisone · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: MAGNESIUM HIGH, BLOOD (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Depressed ocular reflex

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Depressed ocular refl… · thi…73MAGNESIUM HIGH, BLOOD · near73Mopey · near73Muscle contracture · near73Synovitis · near73Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Depressed ocular reflex

Depressed ocular reflex: high death-coded share in the FDA AER plate

Signature read: Depressed ocular reflex's 30.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 22 of 73 reports (30.1% of named reports). Nearest volume peer: MAGNESIUM HIGH, BLOOD (±0 reports). Lead species Dog (54). Lead co-reported drug Prednisone (10).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 54
Cat 17
Rabbit 1
Horse 1

Breeds Most Affected

Domestic Shorthair 11
Retriever - Labrador 10
Crossbred Canine/dog 6
Pug 4
Bulldog - French 3
Beagle 3
Shepherd Dog - German 3
Chihuahua 2
Maltese 2
Boxer (German Boxer) 2

Associated Drugs

Prednisone 10
Gabapentin 10
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 9
Bedinvetmab 8
Carprofen 6
Maropitant Citrate 6
Buprenorphine 5
Ketamine 5
Dexmedetomidine 5
Enrofloxacin 4
Milbemycin Oxime + Spinosad 4
Isoflurane 4
Epinephrine 4
Robenacoxib 4
Lokivetmab Injectable Solution 4
Florfenicol + Mometasone Furoate + Terbinafine 4
Fluid Therapy 4
Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic 4
Butorphanol 3
Pradofloxacin 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Depressed ocular reflex, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (73 here).

Similar death-coded share

Nearest other reactions by death-coded share (30.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Depressed ocular reflex (#1548 of 2,481 by report volume); death-coded 30.1%. PlainBreed reaction plate · death-coded share stamp 30.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →