Reaction profile

The FDA adverse-event record for hypokalaemia

1,741 FDA adverse-event reports reference hypokalaemia (VeDDRA 2418). See the species, breeds, and drugs most associated with it below.

1,741
reports citing this reaction
28.5%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
1,741
Total Reports
496
Deaths
28.5%
Death Rate

Species Most Affected

Dog 1,103
Cat 625
Horse 8
Human 3
Other Canids 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 439
Retriever - Labrador 115
Crossbred Canine/dog 75
Retriever - Golden 52
Domestic Longhair 50
Chihuahua 47
Domestic Mediumhair 34
Terrier - Yorkshire 33
Shih Tzu 33
Shepherd Dog - Australian 29

Associated Drugs

Maropitant Citrate 242
Carprofen 160
Velagliflozin Proline Monohydrate 160
Prednisone 151
Bexagliflozin 123
Trilostane 93
Cefovecin 90
Oclacitinib Maleate 86
Gabapentin 86
Afoxolaner 85
Buprenorphine 75
Moxidectin 66
Ivermectin + Pyrantel As Pamoate Salt 66
Desoxycorticosterone Pivalate 63
Frunevetmab 62
Pyrantel Pamoate;Sarolaner 57
Enrofloxacin 56
Famotidine 55
Desoxycortone Pivalate 54
Fluid Therapy 48

Hypokalaemia Reaction Insights

1,741 reports name Hypokalaemia; 496 recorded a death outcome (28.5% of reported events, not a population-level mortality rate). VeDDRA code: 2418.

By species: Dog (1,103 reports), Cat (625 reports), Horse (8 reports). By breed: Domestic Shorthair (439), Retriever - Labrador (115), Crossbred Canine/dog (75).

Most co-reported drugs: Maropitant Citrate (242 reports), Carprofen (160 reports), Velagliflozin Proline Monohydrate (160 reports), Prednisone (151 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.