Reaction profile

The FDA adverse-event record for hallucination

354 FDA adverse-event reports reference hallucination (VeDDRA 117). See the species, breeds, and drugs most associated with it below.

354
reports citing this reaction
6.5%
death-coded share
Dog
most-affected species
Buprenorphine
most-associated drug
Verify with FDA CVM →
354
Total Reports
23
Deaths
6.5%
Death Rate

Species Most Affected

Dog 240
Cat 111
Horse 2
Monkey 1

Breeds Most Affected

Domestic Shorthair 59
Retriever - Labrador 26
Cat (unknown) 20
Crossbred Canine/dog 17
Chihuahua 14
Pit Bull 10
Collie - Border 9
Domestic Longhair 9
Terrier - Yorkshire 8
Dog (unknown) 8

Associated Drugs

Buprenorphine 64
Milbemycin Oxime + Spinosad 54
Spinosad 29
Pyrantel Pamoate;Sarolaner 24
Afoxolaner 21
Sarolaner 19
Ivermectin 16
Maropitant Citrate 14
Ivermectin + Pyrantel As Pamoate Salt 13
Robenacoxib 11
Butorphanol 10
Isoflurane 10
Selamectin 8
Oclacitinib Maleate 8
Fluralaner Chew Tablets 8
Carprofen 7
Meloxicam 7
Selamectin;Sarolaner 7
Nitenpyram 6
Ketamine 6

Hallucination Reaction Insights

354 reports name Hallucination; 23 recorded a death outcome (6.5% of reported events, not a population-level mortality rate). VeDDRA code: 117.

By species: Dog (240 reports), Cat (111 reports), Horse (2 reports). By breed: Domestic Shorthair (59), Retriever - Labrador (26), Cat (unknown) (20).

Most co-reported drugs: Buprenorphine (64 reports), Milbemycin Oxime + Spinosad (54 reports), Spinosad (29 reports), Pyrantel Pamoate;Sarolaner (24 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.