Hallucination

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VeDDRA Code: 117

354 adverse event reports referencing this reaction

354
Total Reports
23
Deaths
650.0%
Death Rate

Species Most Affected

Dog 240
Cat 111
Horse 2
Monkey 1

Breeds Most Affected

Domestic Shorthair 59
Retriever - Labrador 26
Cat (unknown) 20
Crossbred Canine/dog 17
Chihuahua 14
Pit Bull 10
Collie - Border 9
Domestic Longhair 9
Terrier - Yorkshire 8
Dog (unknown) 8

Associated Drugs

Buprenorphine 64
Milbemycin Oxime + Spinosad 54
Spinosad 29
Pyrantel Pamoate;Sarolaner 24
Afoxolaner 21
Sarolaner 19
Ivermectin 16
Maropitant Citrate 14
Ivermectin + Pyrantel As Pamoate Salt 13
Robenacoxib 11
Butorphanol 10
Isoflurane 10
Selamectin 8
Oclacitinib Maleate 8
Fluralaner Chew Tablets 8
Carprofen 7
Meloxicam 7
Selamectin;Sarolaner 7
Nitenpyram 6
Ketamine 6

Data Summary

Metric Value
Total reports referencing reaction 354
Reports with fatal outcome 23
Case-fatality rate (reported events) 650.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 117.

Hallucination Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 354 adverse event reports that reference Hallucination as a reaction term, including 23 reports with a death outcome — a 650.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 117, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hallucination appears most frequently in reports for Dog (240 reports), Cat (111 reports), Horse (2 reports) — with Dog dominating at 240 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (59), Retriever - Labrador (26), Cat (unknown) (20). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hallucination are Buprenorphine (64 reports), Milbemycin Oxime + Spinosad (54 reports), Spinosad (29 reports), Pyrantel Pamoate;Sarolaner (24 reports), with Buprenorphine appearing alongside this reaction in 64 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial