Reaction profile

The FDA adverse-event record for head tilt - ear disorder

1,782 FDA adverse-event reports reference head tilt - ear disorder (VeDDRA 374). See the species, breeds, and drugs most associated with it below.

1,782
reports citing this reaction
10.8%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
1,782
Total Reports
192
Deaths
10.8%
Death Rate

Species Most Affected

Dog 1,359
Cat 396
Rabbit 9
Horse 8
Cattle 5
Bobcat 1
Donkey 1
Ferret 1
Other Rodents 1
Chicken 1

Breeds Most Affected

Domestic Shorthair 225
Retriever - Labrador 122
Crossbred Canine/dog 100
Chihuahua 60
Shih Tzu 60
Retriever - Golden 57
Domestic (unspecified) 50
Boxer (German Boxer) 49
Bulldog - French 44
Maltese 43

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 349
Milbemycin Oxime + Spinosad 154
Maropitant Citrate 108
Carprofen 91
Spinosad 88
Selamectin 73
Enrofloxacin 69
Prednisone 67
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 63
Betamethasone + Florfenicol + Terbinafine 60
Afoxolaner 52
Gabapentin 44
Trilostane 42
Cefovecin 42
Oclacitinib Maleate 42
Bedinvetmab 41
Genta/Momet/Clotrim Ear Oint 38
Florfenicol, Terbinafine, Betamethasone Acetate 37
Ivermectin + Pyrantel As Pamoate Salt 36
Ear Cleaner 35

Head tilt - ear disorder Reaction Insights

1,782 reports name Head tilt - ear disorder; 192 recorded a death outcome (10.8% of reported events, not a population-level mortality rate). VeDDRA code: 374.

By species: Dog (1,359 reports), Cat (396 reports), Rabbit (9 reports). By breed: Domestic Shorthair (225), Retriever - Labrador (122), Crossbred Canine/dog (100).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (349 reports), Milbemycin Oxime + Spinosad (154 reports), Maropitant Citrate (108 reports), Carprofen (91 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.