INEFFECTIVE, PARASITE(S)

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VeDDRA Code: 99134

18 adverse event reports referencing this reaction

18
Total Reports
2
Deaths
1110.0%
Death Rate

Species Most Affected

Dog 10
Cattle 5
Cat 1
Chicken 1
Bison 1

Breeds Most Affected

Dog (unknown) 7
Cattle (unknown) 2
Crossbred Canine/dog 2
Retriever - Golden 1
Cat (other) 1
Holstein-Friesian also known as Holstein 1
Chicken (unknown) 1
American bison 1
Cattle (other) 1
Mixed (Cattle) 1

Associated Drugs

Milbemycin Oxime + Spinosad 8
Eprinomectin 3
Ivermectin 2
Selamectin 1
Fenbendazol Granules 1
Tylosin 1
Bovine Parainfluenza 3 Virus, Killed Virus + Bovine Respiratory Syncytial Virus, Killed Virus + Bovine Rhinotracheitis Virus, Killed Virus + Bovine Virus Diarrhea Type 1, Killed Virus + Bovine Virus Diarrhea Type 2, Killed Virus + Leptospira Canicola Bacterin + Leptospira Grippotyphosa Bacterin + Leptospira Hardjo Bacterin + Leptospira Icterohaemorrhagiae Bacterin + Leptospira Pomona Bacterin 1
Clostridium Chauvoei + Clostridium Haemolyticum + Clostridium Novyi + Clostridium Perfringens Type C + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1
Spinosad 1
Doramectin 1

Data Summary

Metric Value
Total reports referencing reaction 18
Reports with fatal outcome 2
Case-fatality rate (reported events) 1110.0%
Species observed 5
Breeds observed 10
Drugs associated with reaction 10

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99134.

INEFFECTIVE, PARASITE(S) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 18 adverse event reports that reference INEFFECTIVE, PARASITE(S) as a reaction term, including 2 reports with a death outcome — a 1110.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99134, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

INEFFECTIVE, PARASITE(S) appears most frequently in reports for Dog (10 reports), Cattle (5 reports), Cat (1 reports) — with Dog dominating at 10 entries. Within those species, the breeds most often named alongside this reaction are Dog (unknown) (7), Cattle (unknown) (2), Crossbred Canine/dog (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with INEFFECTIVE, PARASITE(S) are Milbemycin Oxime + Spinosad (8 reports), Eprinomectin (3 reports), Ivermectin (2 reports), Selamectin (1 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 8 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial