Reaction profile

The FDA adverse-event record for pancytopenia

143 FDA adverse-event reports reference pancytopenia (VeDDRA 2114). See the species, breeds, and drugs most associated with it below.

143
reports citing this reaction
30.1%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
143
Total Reports
43
Deaths
30.1%
Death Rate

Species Most Affected

Dog 116
Cat 26
Chicken 1

Breeds Most Affected

Retriever - Labrador 17
Domestic Shorthair 15
Crossbred Canine/dog 13
Schnauzer - Miniature 6
Shepherd Dog - German 5
Shepherd Dog - Australian 4
Pug 4
Beagle 4
Maltese 3
Mixed (Dog) 3

Associated Drugs

Oclacitinib Maleate 25
Cefovecin 15
Doxycycline 14
Maropitant Citrate 12
Fenbendazol Granules 12
Carprofen 9
Enrofloxacin 7
Prednisone 7
Fluralaner Chew Tablets 7
Afoxolaner 6
Anti-Il31 Mab Mcs Lot #1283563 6
Gabapentin 6
Selamectin 5
Buprenorphine 5
Moxidectin 5
Estriol Tablets 5
Tramadol 4
Trilostane 4
Sarolaner 4
Fluralaner 13.64% 12-Week Chew 4

Pancytopenia Reaction Insights

143 reports name Pancytopenia; 43 recorded a death outcome (30.1% of reported events, not a population-level mortality rate). VeDDRA code: 2114.

By species: Dog (116 reports), Cat (26 reports), Chicken (1 reports). By breed: Retriever - Labrador (17), Domestic Shorthair (15), Crossbred Canine/dog (13).

Most co-reported drugs: Oclacitinib Maleate (25 reports), Cefovecin (15 reports), Doxycycline (14 reports), Maropitant Citrate (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.