Reaction profile

The FDA adverse-event record for panic

122 FDA adverse-event reports reference panic (VeDDRA 2610). See the species, breeds, and drugs most associated with it below.

122
reports citing this reaction
10.7%
death-coded share
Dog
most-affected species
Fluralaner 13.64% 12-Week Chew
most-associated drug
Verify with FDA CVM →
122
Total Reports
13
Deaths
10.7%
Death Rate

Species Most Affected

Dog 73
Cat 47
Donkey 1
Horse 1

Breeds Most Affected

Domestic Shorthair 19
Crossbred Canine/dog 10
Cat (unknown) 8
Retriever - Labrador 7
Terrier - Yorkshire 6
Chihuahua 6
Cat (other) 5
Retriever - Golden 5
Domestic Mediumhair 3
Spaniel (unspecified) 3

Associated Drugs

Fluralaner 13.64% 12-Week Chew 15
Buprenorphine 14
Gabapentin 10
Fluralaner/Moxidectin Spot-On 9
Pyrantel Pamoate;Sarolaner 9
Fluralaner Spot-On Solution 7
Ivermectin + Pyrantel As Pamoate Salt 6
Maropitant Citrate 6
Afoxolaner 6
Moxidectin 5
Selamectin 5
Selamectin;Sarolaner 5
Imidacloprid + Moxidectin 5
Diphenhydramine 4
Isoflurane 4
Robenacoxib 4
Eprinomectin + Esafoxolaner + Praziquantel 4
Bedinvetmab 4
Sarolaner 3
Polysulfated Glycosaminoglycan 3

Panic Reaction Insights

122 reports name Panic; 13 recorded a death outcome (10.7% of reported events, not a population-level mortality rate). VeDDRA code: 2610.

By species: Dog (73 reports), Cat (47 reports), Donkey (1 reports). By breed: Domestic Shorthair (19), Crossbred Canine/dog (10), Cat (unknown) (8).

Most co-reported drugs: Fluralaner 13.64% 12-Week Chew (15 reports), Buprenorphine (14 reports), Gabapentin (10 reports), Fluralaner/Moxidectin Spot-On (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.