Reaction profile

The FDA adverse-event record for pr-multiple sites, congestion

43 FDA reports name pr-multiple sites, congestion, a lower-volume reaction in the CVM extract (VeDDRA 99646). Plate stamps and neighbourhood peers follow.

#1821 of 2,481
by report volume (all reactions)
43
reports citing this reaction
100.0%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-MULTIPLE SITES, CONGESTION has 43 reports now versus 42 in that prior snapshot: 1 more (2.4%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-MULTIPLE SITES, CONGESTION changes

FDA AER · VeDDRA plate

Code 99646 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 43 reports
  • DEATH-HOT 100.0%
  • MID-PACK #1821/2481
  • PHOTO-FINISH Application site numb…
  • SPECIES-DOG Dog · 32
  • DRUG-LEAD Carprofen · 7
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site numbness (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-MULTIPLE SITES, CONGESTION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site numb… · near43Elevated AST · near43INEFFECTIVE, PINWORMS · near43INEFFECTIVE, STOMACH… · near43PR-MULTIPLE SITES, CO… · thi…43Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-MULTIPLE SITES, CONGESTION

PR-MULTIPLE SITES, CONGESTION: high death-coded share in the FDA AER plate

Signature read: PR-MULTIPLE SITES, CONGESTION's 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 43 named reports in the openFDA extract. Death-coded share is upper-third: 43 of 43 reports (100.0% of named reports). Nearest volume peer: Application site numbness (±0 reports). Lead species Dog (32). Lead co-reported drug Carprofen (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 32
Cat 10
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 4
Domestic (unspecified) 3
Retriever - Labrador 3
Domestic Shorthair 3
Terrier - Yorkshire 3
Siamese 2
Spaniel - King Charles Cavalier 1
Terrier - Bull 1
Mountain Dog - Bernese 1
Newfoundland 1

Associated Drugs

Carprofen 7
Moxidectin 7
Maropitant Citrate 4
Spinosad 3
Butorphanol Tartrate 3
Diphenhydramine Hcl 3
Robenacoxib 3
Deracoxib 2
Enrofloxacin 2
Maropitant 2
Dextrose 2
Famotidine 2
Glycosaminoglycan Polysulfate 2
Acepromazine 2
Ketamine 2
Milbemycin Oxime + Spinosad 2
Tiletamine, Zolazepam 1
Melarsomine Dihydrochloride 1
Amoxicillin, Clavulanate 1
Ormetoprim, Sulfadimethoxine 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-MULTIPLE SITES, CONGESTION (#1821 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →