Reaction profile

The FDA adverse-event record for pr-multiple sites, congestion

42 FDA adverse-event reports reference pr-multiple sites, congestion (VeDDRA 99646). See the species, breeds, and drugs most associated with it below.

42
reports citing this reaction
100.0%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
42
Total Reports
42
Deaths
100.0%
Death Rate

Species Most Affected

Dog 31
Cat 10
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 4
Domestic (unspecified) 3
Retriever - Labrador 3
Domestic Shorthair 3
Terrier - Yorkshire 3
Siamese 2
Spaniel - King Charles Cavalier 1
Terrier - Bull 1
Mountain Dog - Bernese 1
Newfoundland 1

Associated Drugs

Moxidectin 7
Carprofen 6
Maropitant Citrate 4
Spinosad 3
Butorphanol Tartrate 3
Diphenhydramine Hcl 3
Robenacoxib 3
Deracoxib 2
Enrofloxacin 2
Dextrose 2
Famotidine 2
Glycosaminoglycan Polysulfate 2
Acepromazine 2
Ketamine 2
Milbemycin Oxime + Spinosad 2
Tiletamine, Zolazepam 1
Melarsomine Dihydrochloride 1
Ormetoprim, Sulfadimethoxine 1
Imidacloprid, Moxidectin 1
Amoxicillin, Clavulanate 1

PR-MULTIPLE SITES, CONGESTION Reaction Insights

42 reports name PR-MULTIPLE SITES, CONGESTION; 42 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). VeDDRA code: 99646.

By species: Dog (31 reports), Cat (10 reports), Cattle (1 reports). By breed: Crossbred Canine/dog (4), Domestic (unspecified) (3), Retriever - Labrador (3).

Most co-reported drugs: Moxidectin (7 reports), Carprofen (6 reports), Maropitant Citrate (4 reports), Spinosad (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.