Reaction profile

The FDA adverse-event record for neoplasm bleeding

11 FDA adverse-event reports reference neoplasm bleeding (VeDDRA 99938). See the species, breeds, and drugs most associated with it below.

11
reports citing this reaction
63.6%
death-coded share
Dog
most-affected species
Toceranib Phosphate
most-associated drug
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11
Total Reports
7
Deaths
63.6%
Death Rate

Species Most Affected

Dog 10
Horse 1

Breeds Most Affected

Retriever - Labrador 2
Bichon Frise 1
Spaniel - Cocker American 1
Dalmatian 1
Warmblood - Dutch 1
Terrier - Cairn 1
Shih Tzu 1
Shepherd Dog - German 1
Mixed (Dog) 1
Dog (unknown) 1

Associated Drugs

Toceranib Phosphate 3
Trilostane 3
Oclacitinib Maleate 3
Prednisone 2
Cyclosporine 1
Carprofen 1
Diphenhydramine Hcl 1
Famotidine 1
Omeprazole 37% Oral Paste 1
Deracoxib 1
Furosemide 1
Metronidazole 1
Clindamycin 1
Omega-3 1
Lysozyme & Lactoferrin 1
Ivermectin/Pyrantel 1

NEOPLASM BLEEDING Reaction Insights

11 reports name NEOPLASM BLEEDING; 7 recorded a death outcome (63.6% of reported events, not a population-level mortality rate). VeDDRA code: 99938.

By species: Dog (10 reports), Horse (1 reports). By breed: Retriever - Labrador (2), Bichon Frise (1), Spaniel - Cocker American (1).

Most co-reported drugs: Toceranib Phosphate (3 reports), Trilostane (3 reports), Oclacitinib Maleate (3 reports), Prednisone (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.