Reaction profile

The FDA adverse-event record for myopathy

32 FDA adverse-event reports reference myopathy (VeDDRA 610). See the species, breeds, and drugs most associated with it below.

32
reports citing this reaction
34.4%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
32
Total Reports
11
Deaths
34.4%
Death Rate

Species Most Affected

Dog 23
Horse 3
Pig 2
Cat 2
Bison 1
Monkey 1

Breeds Most Affected

Retriever - Labrador 3
Maltese 2
Pig (unknown) 2
Domestic Shorthair 2
Terrier - Jack Russell 2
Doberman Pinscher 1
Poodle - Toy 1
Bulldog - French 1
Spaniel - Springer English 1
Spitz - American Eskimo Dog 1

Associated Drugs

Trilostane 5
Bedinvetmab 5
Grapiprant 3
Pimobendan 3
Furosemide 3
Narasin 2
Fluralaner Chew Tablets 2
Carprofen 2
Enrofloxacin 2
Isoflurane 2
Gabapentin 2
Firocoxib 227 Mg Chewable 1
Spinosad 1
Milbemycin Oxime + Spinosad 1
Tiamulin Hydrogen Fumarate 1
Meloxicam 1
Dexmedetomidine Hydrochloride 1
Atipamezole Hydrochloride 1
Oxfendazole 1
Clostridium Chauvoei + Clostridium Novyi + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1

Myopathy Reaction Insights

32 reports name Myopathy; 11 recorded a death outcome (34.4% of reported events, not a population-level mortality rate). VeDDRA code: 610.

By species: Dog (23 reports), Horse (3 reports), Pig (2 reports). By breed: Retriever - Labrador (3), Maltese (2), Pig (unknown) (2).

Most co-reported drugs: Trilostane (5 reports), Bedinvetmab (5 reports), Grapiprant (3 reports), Pimobendan (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.