Reaction profile

The FDA adverse-event record for myopathy

33 FDA reports name myopathy, a lower-volume reaction in the CVM extract (VeDDRA 610). Plate stamps and neighbourhood peers follow.

#1945 of 2,481
by report volume (all reactions)
33
reports citing this reaction
33.3%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Myopathy has 33 reports now versus 33 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Myopathy changes

FDA AER · VeDDRA plate

Code 610 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 33 reports
  • DEATH-HOT 33.3%
  • LOWER-Q #1945/2481
  • PHOTO-FINISH Abnormal dexamethason…
  • SPECIES-DOG Dog · 24
  • DRUG-LEAD Trilostane · 5
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Myopathy

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal dexamethason… · near33Burning mouth sensati… · near33Decreased number of s… · near33Displaced abomasum · near33Myopathy · this reaction33Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Myopathy

Myopathy: high death-coded share in the FDA AER plate

Signature read: Myopathy's 33.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 33 named reports in the openFDA extract. Death-coded share is upper-third: 11 of 33 reports (33.3% of named reports). Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports). Lead species Dog (24). Lead co-reported drug Trilostane (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 24
Horse 3
Pig 2
Cat 2
Bison 1
Monkey 1

Breeds Most Affected

Retriever - Labrador 3
Maltese 2
Pig (unknown) 2
Domestic Shorthair 2
Terrier - Jack Russell 2
Doberman Pinscher 1
Poodle - Toy 1
Bulldog - French 1
Spaniel - Springer English 1
Spitz - American Eskimo Dog 1

Associated Drugs

Trilostane 5
Bedinvetmab 5
Grapiprant 3
Pimobendan 3
Furosemide 3
Narasin 2
Fluralaner Chew Tablets 2
Carprofen 2
Enrofloxacin 2
Isoflurane 2
Gabapentin 2
Firocoxib 227 Mg Chewable 1
Spinosad 1
Milbemycin Oxime + Spinosad 1
Tiamulin Hydrogen Fumarate 1
Meloxicam 1
Dexmedetomidine Hydrochloride 1
Atipamezole Hydrochloride 1
Oxfendazole 1
Clostridium Chauvoei + Clostridium Novyi + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Myopathy (#1945 of 2,481 by report volume); death-coded 33.3%. PlainBreed reaction plate · death-coded share stamp 33.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →