Reaction profile

The FDA adverse-event record for thromboemboli

75 FDA adverse-event reports reference thromboemboli (VeDDRA 155). See the species, breeds, and drugs most associated with it below.

75
reports citing this reaction
73.3%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
75
Total Reports
55
Deaths
73.3%
Death Rate

Species Most Affected

Dog 38
Cat 34
Cattle 2
Pig 1

Breeds Most Affected

Domestic Shorthair 21
Chihuahua 4
Retriever - Golden 3
Domestic Longhair 3
Domestic Mediumhair 3
Retriever - Labrador 3
Beagle 2
Siamese 2
Terrier - West Highland White 2
Shepherd Dog - German 2

Associated Drugs

Trilostane 7
Maropitant Citrate 7
Frunevetmab 7
Meloxicam 6
Robenacoxib 5
Oclacitinib Maleate 5
Melarsomine Dihydrochloride 5
Gabapentin 5
Grapiprant 4
Ketamine 4
Isoflurane 4
Carprofen 4
Buprenorphine 4
Bedinvetmab 4
Spinosad 3
Enrofloxacin 3
Recombinant Human Insulin 3
Afoxolaner 3
Cefazolin 3
Moxidectin 3

Thromboemboli Reaction Insights

75 reports name Thromboemboli; 55 recorded a death outcome (73.3% of reported events, not a population-level mortality rate). VeDDRA code: 155.

By species: Dog (38 reports), Cat (34 reports), Cattle (2 reports). By breed: Domestic Shorthair (21), Chihuahua (4), Retriever - Golden (3).

Most co-reported drugs: Trilostane (7 reports), Maropitant Citrate (7 reports), Frunevetmab (7 reports), Meloxicam (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.