Reaction profile

The FDA adverse-event record for cardiac tamponade

Name: Cardiac tamponade - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

24 FDA reports name cardiac tamponade, a lower-volume reaction in the CVM extract (VeDDRA 236). Plate stamps and neighbourhood peers follow.

#2082 of 2,481
by report volume (all reactions): 24
reports citing this reaction: 83.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cardiac tamponade has 24 reports now versus 24 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cardiac tamponade changes

FDA AER · VeDDRA plate

Code 236 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 24 reports
DEATH-HOT 83.3%
LOWER-Q #2082/2481
PHOTO-FINISH Acute pancreatitis
SPECIES-DOG Dog · 22
DRUG-LEAD Milbemycin Oxime… · 5
DESK-WIDE 18 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Acute pancreatitis (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Cardiac tamponade

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Cardiac tamponade

Cardiac tamponade: high death-coded share in the FDA AER plate

Signature read: Cardiac tamponade's 83.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 24 named reports in the openFDA extract. Death-coded share is upper-third: 20 of 24 reports (83.3% of named reports). Nearest volume peer: Acute pancreatitis (±0 reports). Lead species Dog (22). Lead co-reported drug Milbemycin Oxime + Spinosad (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 22

Cattle 1

Snake 1

Breeds Most Affected

Siberian Husky 3

Retriever - Golden 3

Shepherd Dog - German 2

Shepherd Dog - Australian 2

Cattle (other) 1

Terrier - Bull - American Pit 1

Greyhound 1

Crossbred Canine/dog 1

Akita 1

Collie - Border 1

Associated Drugs

Milbemycin Oxime + Spinosad 5

Carprofen 2

Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 2

Enrofloxacin 2

Spinosad 2

Moxidectin 2

Maropitant Citrate 2

Ivermectin + Pyrantel As Pamoate Salt 2

Pyrantel Pamoate;Sarolaner 2

Monensin Sodium 1

Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 1

Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 1

Doxycycline 1

Rabies Vaccine 1

Distemper Vaccine 1

Bordetella Vaccine 1

Canine Influenza Virus H3N8, Kv 1

Canine Influenza Virus H3N2, Kv 1

Cefazolin 1

Afoxolaner 68 Mg Chewable Tablets 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cardiac tamponade (#2082 of 2,481 by report volume); death-coded 83.3%. PlainBreed reaction plate · death-coded share stamp 83.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →