Reaction profile

The FDA adverse-event record for eye inflammation nos

126 FDA adverse-event reports reference eye inflammation nos (VeDDRA 1456). See the species, breeds, and drugs most associated with it below.

126
reports citing this reaction
12.7%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
126
Total Reports
16
Deaths
12.7%
Death Rate

Species Most Affected

Dog 97
Cat 21
Human 4
Cattle 1
Turkey 1
Horse 1
Pig 1

Breeds Most Affected

Domestic Shorthair 12
Retriever - Labrador 12
Chihuahua 9
Boxer (German Boxer) 7
Retriever - Golden 5
Shih Tzu 5
Unknown 4
Domestic Longhair 4
Maltese 4
Crossbred Canine/dog 3

Associated Drugs

Milbemycin Oxime + Spinosad 24
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Afoxolaner 7
Fluralaner Chew Tablets 7
Oclacitinib Maleate 5
Maropitant Citrate 5
Diphenhydramine 5
Tobramycin 4
Imidacloprid + Moxidectin 4
Moxidectin 4
Prednisone 4
Trilostane 4
Gabapentin 4
Bordetella Vaccine 3
Spinosad 3
Selamectin 3
Cefovecin 3
Carprofen 3
Buprenorphine 3
Famotidine 3

Eye inflammation NOS Reaction Insights

126 reports name Eye inflammation NOS; 16 recorded a death outcome (12.7% of reported events, not a population-level mortality rate). VeDDRA code: 1456.

By species: Dog (97 reports), Cat (21 reports), Human (4 reports). By breed: Domestic Shorthair (12), Retriever - Labrador (12), Chihuahua (9).

Most co-reported drugs: Milbemycin Oxime + Spinosad (24 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (10 reports), Afoxolaner (7 reports), Fluralaner Chew Tablets (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.