Reaction profile

The FDA adverse-event record for pr-colon, lesion(s)

Name: PR-COLON, LESION(S) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

56 FDA reports name pr-colon, lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99607). Plate stamps and neighbourhood peers follow.

#1685 of 2,481
by report volume (all reactions): 56
reports citing this reaction: 85.7%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-COLON, LESION(S) has 56 reports now versus 55 in that prior snapshot: 1 more (1.8%).

Report change: +1
Death-coded reports: +1
Death-coded share: +0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-COLON, LESION(S) changes

FDA AER · VeDDRA plate

Code 99607 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-LOW 56 reports
DEATH-HOT 85.7%
MID-PACK #1685/2481
PHOTO-FINISH Abdominal oedema
SPECIES-DOG Dog · 35
DRUG-LEAD Meloxicam · 6
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal oedema (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-COLON, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around PR-COLON, LESION(S)

PR-COLON, LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-COLON, LESION(S)'s 85.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 56 named reports in the openFDA extract. Death-coded share is upper-third: 48 of 56 reports (85.7% of named reports). Nearest volume peer: Abdominal oedema (±0 reports). Lead species Dog (35). Lead co-reported drug Meloxicam (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 35

Cat 12

Horse 6

Cattle 2

Donkey 1

Breeds Most Affected

Boxer (German Boxer) 7

Domestic (unspecified) 4

Crossbred Canine/dog 4

Domestic Shorthair 4

Retriever - Labrador 3

Chihuahua 3

Quarter Horse 3

Persian 2

Manx 2

Doberman Pinscher 2

Associated Drugs

Meloxicam 6

Carprofen 6

Cefovecin Sodium 5

Moxidectin 5

Maropitant 4

Deracoxib 4

Enrofloxacin 3

Firocoxib 2

Robenacoxib 2

Cefovecin 2

Maropitant Citrate 2

Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 2

Sucralfate 2

Tramadol 2

Hetastarch 2

Fluralaner Chew Tablets 2

Milbemycin Oxime + Praziquantel 2

Ivermectin 1

Spinosad 1

Imidacloprid, Moxidectin 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for PR-COLON, LESION(S), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (56 here).

Abdominal oedema 56 Abnormal oestrus NOS 56 High leg gait 56 Indigestion 56

Similar death-coded share

Nearest other reactions by death-coded share (85.7% here), distinct from the volume row.

Bloody foam in mouth and nose 84.9% Myocarditis 86.6% Disseminated intravascular coagulation 84.6% PR-SMALL INTESTINE, LESION(S) 84.6%

What to do with this reaction

Compare PR-COLON, LESION's report profile against similar reactions nationwide. See similar reactions
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-COLON, LESION(S) (#1685 of 2,481 by report volume); death-coded 85.7%. PlainBreed reaction plate · death-coded share stamp 85.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →