Reaction profile

The FDA adverse-event record for claw / hoof / nail disorder nos

273 FDA adverse-event reports reference claw / hoof / nail disorder nos (VeDDRA 1919). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#906 of 2,481
by report volume (all reactions)
273
reports citing this reaction
15.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Claw / hoof / nail disorder NOS has 273 reports now versus 267 in that prior snapshot: 6 more (2.2%).

Report change
+6
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Claw / hoof / nail disorder NOS changes

FDA AER · VeDDRA plate

Code 1919 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 273 reports
  • DEATH-ELEV 15.8%
  • MID-PACK #906/2481
  • PHOTO-FINISH Ear canal inflammation
  • SPECIES-DOG Dog · 165
  • DRUG-LEAD Oclacitinib Malea… · 35
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Ear canal inflammation (±1 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Claw / hoof / nail disorder NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bad taste · near278Rigidity of limbs · near277Claw / hoof / nail di… · thi…273Ear canal inflammation · near272Other blood disorder… · near269Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Claw / hoof / nail disorder NOS

What the FDA AER plate says about Claw / hoof / nail disorder NOS

Signature read: 43 death-coded reports is a heavy tail count for Claw / hoof / nail disorder NOS in the CVM extract. Report volume sits in the middle third of the reaction corpus. 43 of 273 reports were death-coded (15.8% of named reports, not a population mortality rate). Nearest volume peer: Ear canal inflammation (±1 reports). Lead species Dog (165). Lead co-reported drug Oclacitinib Maleate (35).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 165
Cattle 36
Cat 30
Horse 29
Pig 5
Human 5
Other Camelids 1
Chicken 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 15
Retriever - Labrador 14
Retriever - Golden 13
Shepherd Dog - German 12
Crossbred Bovine/Cattle 10
Cattle (unknown) 8
Crossbred Canine/dog 8
Holstein-Friesian also known as Holstein 7
Quarter Horse 7
Pit Bull 6

Associated Drugs

Oclacitinib Maleate 35
Bedinvetmab 28
Carprofen 20
Milbemycin Oxime + Spinosad 19
Pergolide Mesylate 16
Afoxolaner 14
Tylosin Phosphate 13
Fluralaner Chew Tablets 11
Cefovecin Sodium 10
Moxidectin 10
Anti-Il31 Mab Mcs Lot #1283563 10
Gabapentin 10
Monensin Sodium 9
Milbemycin Oxime + Praziquantel 9
Meloxicam 8
Zilpaterol 8
Cyclosporine 8
Cefovecin 8
Ivermectin + Pyrantel As Pamoate Salt 8
Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Claw / hoof / nail disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (273 here).

Similar death-coded share

Nearest other reactions by death-coded share (15.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Claw / hoof / nail disorder NOS (#906 of 2,481 by report volume); death-coded 15.8%. PlainBreed reaction plate · death-coded report count stamp 43 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →