Reaction profile

The FDA adverse-event record for mass nos

450 FDA adverse-event reports reference mass nos (VeDDRA 2886). See the species, breeds, and drugs most associated with it below.

450
reports citing this reaction
27.6%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
450
Total Reports
124
Deaths
27.6%
Death Rate

Species Most Affected

Dog 407
Cat 43

Breeds Most Affected

Retriever - Labrador 61
Dog (unknown) 32
Domestic Shorthair 30
Crossbred Canine/dog 27
Terrier - Bull - American Pit 19
Retriever - Golden 18
Chihuahua 15
Pit Bull 14
Boxer (German Boxer) 14
Beagle 13

Associated Drugs

Bedinvetmab 124
Oclacitinib Maleate 59
Gabapentin 56
Carprofen 41
Tigilanol Tiglate 40
Prednisone 37
Maropitant Citrate 36
Diphenhydramine 30
Trilostane 28
Milbemycin Oxime + Praziquantel 24
Famotidine 23
Fluralaner 13.64% 12-Week Chew 20
Grapiprant 18
Butorphanol 18
Doxycycline 17
Rabies Vaccine 16
Metronidazole 15
Frunevetmab 15
Afoxolaner 15
Pyrantel Pamoate;Sarolaner 15

Mass NOS Reaction Insights

450 reports name Mass NOS; 124 recorded a death outcome (27.6% of reported events, not a population-level mortality rate). VeDDRA code: 2886.

By species: Dog (407 reports), Cat (43 reports). By breed: Retriever - Labrador (61), Dog (unknown) (32), Domestic Shorthair (30).

Most co-reported drugs: Bedinvetmab (124 reports), Oclacitinib Maleate (59 reports), Gabapentin (56 reports), Carprofen (41 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.