Reaction profile

The FDA adverse-event record for mass nos

566 FDA reports name mass nos, a high-volume reaction in the CVM extract (VeDDRA 2886). Plate stamps and neighbourhood peers follow.

#595 of 2,481
by report volume (all reactions)
566
reports citing this reaction
26.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Mass NOS has 566 reports now versus 526 in that prior snapshot: 40 more (7.6%).

Report change
+40
Death-coded reports
+4
Death-coded share
−1.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Mass NOS changes

FDA AER · VeDDRA plate

Code 2886 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 566 reports
  • DEATH-HOT 26.1%
  • UPPER-Q #595/2481
  • PHOTO-FINISH Joint pain
  • SPECIES-DOG Dog · 509
  • DRUG-LEAD Bedinvetmab · 146
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Joint pain (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Mass NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Head down · near571Joint pain · near566Mass NOS · this reaction566Oral bleeding · near566Regenerative anaemia · near566Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Mass NOS

Mass NOS: high death-coded share in the FDA AER plate

Signature read: 148 death-coded reports is a heavy tail count for Mass NOS in the CVM extract. Report volume is upper-third scale: 566 named reports in the openFDA extract. Death-coded share is upper-third: 148 of 566 reports (26.1% of named reports). Nearest volume peer: Joint pain (±0 reports). Lead species Dog (509). Lead co-reported drug Bedinvetmab (146).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 509
Cat 56
Cattle 1

Breeds Most Affected

Retriever - Labrador 68
Dog (unknown) 38
Domestic Shorthair 36
Crossbred Canine/dog 32
Terrier - Bull - American Pit 28
Retriever - Golden 26
Pit Bull 19
Chihuahua 19
Beagle 18
Boxer (German Boxer) 17

Associated Drugs

Bedinvetmab 146
Oclacitinib Maleate 88
Gabapentin 66
Carprofen 50
Prednisone 49
Tigilanol Tiglate 44
Maropitant Citrate 41
Milbemycin Oxime + Praziquantel 34
Diphenhydramine 32
Trilostane 29
Ilunocitinib 26
Butorphanol 25
Grapiprant 25
Famotidine 24
Doxycycline 23
Afoxolaner 23
Fluralaner 13.64% 12-Week Chew 22
Pyrantel Pamoate;Sarolaner 22
Frunevetmab 21
Anti-Il31 Mab Mcs Lot #1283563 21

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Mass NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (566 here).

Similar death-coded share

Nearest other reactions by death-coded share (26.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Mass NOS (#595 of 2,481 by report volume); death-coded 26.1%. PlainBreed reaction plate · death-coded report count stamp 148 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →