Reaction profile

The FDA adverse-event record for gall bladder & bile duct disorder nos

883 FDA reports name gall bladder & bile duct disorder nos, a high-volume reaction in the CVM extract (VeDDRA 480). Plate stamps and neighbourhood peers follow.

#430 of 2,481
by report volume (all reactions)
883
reports citing this reaction
33.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Gall bladder & bile duct disorder NOS has 883 reports now versus 863 in that prior snapshot: 20 more (2.3%).

Report change
+20
Death-coded reports
+2
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Gall bladder & bile duct disorder NOS changes

FDA AER · VeDDRA plate

Code 480 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 883 reports
  • DEATH-HOT 33.2%
  • UPPER-Q #430/2481
  • PHOTO-FINISH Incoordination
  • SPECIES-DOG Dog · 828
  • DRUG-LEAD Trilostane · 190
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Incoordination (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Gall bladder & bile duct disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Elevated liver enzyme… · near887Gall bladder & bile d… · thi…883Incoordination · near882Intestinal disorder N… · near881Closure, Missing · near878Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Gall bladder & bile duct disorder NOS

Gall bladder & bile duct disorder NOS: high death-coded share in the FDA AER plate

Signature read: 293 death-coded reports is a heavy tail count for Gall bladder & bile duct disorder NOS in the CVM extract. Report volume is upper-third scale: 883 named reports in the openFDA extract. Death-coded share is upper-third: 293 of 883 reports (33.2% of named reports). Nearest volume peer: Incoordination (±1 reports). Lead species Dog (828). Lead co-reported drug Trilostane (190).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 828
Cat 51
Cattle 2
Human 1
Unknown 1

Breeds Most Affected

Retriever - Labrador 86
Crossbred Canine/dog 64
Chihuahua 37
Shih Tzu 32
Terrier - Yorkshire 30
Beagle 25
Domestic Shorthair 24
Maltese 23
Terrier (unspecified) 22
Schnauzer - Miniature 21

Associated Drugs

Trilostane 190
Maropitant Citrate 138
Carprofen 131
Milbemycin Oxime + Spinosad 84
Metronidazole 45
Moxidectin 43
Oclacitinib Maleate 41
Famotidine 38
Gabapentin 36
Enrofloxacin 34
Spinosad 33
Fluralaner Chew Tablets 32
Ursodiol 31
Buprenorphine 28
Fluralaner 13.64% 12-Week Chew 28
Afoxolaner 26
Bedinvetmab 26
Grapiprant 25
Prednisone 23
Tramadol 22

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Gall bladder & bile duct disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (883 here).

Similar death-coded share

Nearest other reactions by death-coded share (33.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Gall bladder & bile duct disorder NOS (#430 of 2,481 by report volume); death-coded 33.2%. PlainBreed reaction plate · death-coded report count stamp 293 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →