Reaction profile

The FDA adverse-event record for lameness

3,718 FDA adverse-event reports reference lameness (VeDDRA 615). See the species, breeds, and drugs most associated with it below.

3,718
reports citing this reaction
17.5%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
3,718
Total Reports
651
Deaths
17.5%
Death Rate

Species Most Affected

Dog 2,781
Cat 344
Horse 263
Cattle 213
Pig 76
Chicken 14
Turkey 7
Unknown 5
Sheep 5
Human 2

Breeds Most Affected

Retriever - Labrador 434
Crossbred Canine/dog 222
Domestic Shorthair 175
Retriever - Golden 147
Shepherd Dog - German 122
Dog (unknown) 117
Boxer (German Boxer) 95
Chihuahua 63
Terrier - Bull - American Pit 63
Pit Bull 62

Associated Drugs

Bedinvetmab 451
Carprofen 395
Gabapentin 270
Milbemycin Oxime + Spinosad 210
Oclacitinib Maleate 171
Afoxolaner 161
Moxidectin 151
Tigilanol Tiglate 143
Prednisone 139
Maropitant Citrate 129
Fluralaner Chew Tablets 107
Frunevetmab 105
Trilostane 92
Enrofloxacin 87
Tramadol 84
Toceranib Phosphate 82
Polysulfated Glycosaminoglycan 79
Milbemycin Oxime + Praziquantel 74
Hyaluronate Sodium 73
Monensin Sodium 73

Lameness Reaction Insights

3,718 reports name Lameness; 651 recorded a death outcome (17.5% of reported events, not a population-level mortality rate). VeDDRA code: 615.

By species: Dog (2,781 reports), Cat (344 reports), Horse (263 reports). By breed: Retriever - Labrador (434), Crossbred Canine/dog (222), Domestic Shorthair (175).

Most co-reported drugs: Bedinvetmab (451 reports), Carprofen (395 reports), Gabapentin (270 reports), Milbemycin Oxime + Spinosad (210 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.