Reaction profile

The FDA adverse-event record for throat irritation

157 FDA adverse-event reports reference throat irritation (VeDDRA 1836). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1161 of 2,481
by report volume (all reactions)
157
reports citing this reaction
5.7%
death-coded share
Human
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Throat irritation has 157 reports now versus 157 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Throat irritation changes

FDA AER · VeDDRA plate

Code 1836 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 157 reports
  • DEATH-PAR 5.7%
  • MID-PACK #1161/2481
  • PHOTO-FINISH Accidental drug intak…
  • SPECIES-HUMAN Human · 83
  • DRUG-LEAD Selamectin · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Accidental drug intake by child (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Throat irritation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site dry… · near158Accidental drug intak… · near157Splenic neoplasm NOS · near157Throat irritation · this rea…157Abnormal necropsy fin… · near156Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Throat irritation

Throat irritation: low death-coded share in the FDA AER plate

Signature read: Throat irritation's 5.7% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 9 of 157 reports (5.7% of named reports). Nearest volume peer: Accidental drug intake by child (±0 reports). Lead species Human (83). Lead co-reported drug Selamectin (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Selamectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 83
Dog 56
Cat 12
Horse 4
Goat 1
Cattle 1

Breeds Most Affected

Unknown 84
Domestic Shorthair 8
Retriever - Labrador 7
Retriever - Golden 5
Chihuahua 4
Boxer (German Boxer) 3
Horse (unknown) 3
Shih Tzu 2
Spaniel - King Charles Cavalier 2
Maltese 2

Associated Drugs

Selamectin 14
Milbemycin Oxime + Spinosad 12
Imidacloprid + Moxidectin 10
Maropitant Citrate 9
Afoxolaner 9
Spinosad 7
Moxidectin 7
Fluralaner Spot-On Solution 7
Ivermectin + Pyrantel As Pamoate Salt 5
Emodepside + Praziquantel 4
Fluralaner Chew Tablets 4
Fluralaner 13.64% 12-Week Chew 4
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 3
Oclacitinib Maleate 3
Prednisone 3
Enrofloxacin 3
Selamectin;Sarolaner 3
Fluralaner/Moxidectin Spot-On 3
Milbemycin Oxime + Praziquantel 3
Lotilaner 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Throat irritation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (5.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Throat irritation (#1161 of 2,481 by report volume); death-coded 5.7%. PlainBreed reaction plate · death-coded share stamp 5.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →