Reaction profile

The FDA adverse-event record for throat irritation

156 FDA adverse-event reports reference throat irritation (VeDDRA 1836). See the species, breeds, and drugs most associated with it below.

156
reports citing this reaction
5.1%
death-coded share
Human
most-affected species
Selamectin
most-associated drug
Verify with FDA CVM →
156
Total Reports
8
Deaths
5.1%
Death Rate

Species Most Affected

Human 82
Dog 56
Cat 12
Horse 4
Goat 1
Cattle 1

Breeds Most Affected

Unknown 83
Domestic Shorthair 8
Retriever - Labrador 7
Retriever - Golden 5
Chihuahua 4
Boxer (German Boxer) 3
Horse (unknown) 3
Shih Tzu 2
Spaniel - King Charles Cavalier 2
Maltese 2

Associated Drugs

Selamectin 14
Milbemycin Oxime + Spinosad 12
Imidacloprid + Moxidectin 10
Maropitant Citrate 9
Afoxolaner 9
Spinosad 7
Moxidectin 7
Fluralaner Spot-On Solution 7
Ivermectin + Pyrantel As Pamoate Salt 5
Emodepside + Praziquantel 4
Fluralaner Chew Tablets 4
Fluralaner 13.64% 12-Week Chew 4
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 3
Oclacitinib Maleate 3
Prednisone 3
Enrofloxacin 3
Selamectin;Sarolaner 3
Milbemycin Oxime + Praziquantel 3
Lotilaner 3
Bedinvetmab 3

Throat irritation Reaction Insights

156 reports name Throat irritation; 8 recorded a death outcome (5.1% of reported events, not a population-level mortality rate). VeDDRA code: 1836.

By species: Human (82 reports), Dog (56 reports), Cat (12 reports). By breed: Unknown (83), Domestic Shorthair (8), Retriever - Labrador (7).

Most co-reported drugs: Selamectin (14 reports), Milbemycin Oxime + Spinosad (12 reports), Imidacloprid + Moxidectin (10 reports), Maropitant Citrate (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.