Throat irritation

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VeDDRA Code: 1836

156 adverse event reports referencing this reaction

156
Total Reports
8
Deaths
510.0%
Death Rate

Species Most Affected

Human 82
Dog 56
Cat 12
Horse 4
Goat 1
Cattle 1

Breeds Most Affected

Unknown 83
Domestic Shorthair 8
Retriever - Labrador 7
Retriever - Golden 5
Chihuahua 4
Boxer (German Boxer) 3
Horse (unknown) 3
Shih Tzu 2
Spaniel - King Charles Cavalier 2
Maltese 2

Associated Drugs

Selamectin 14
Milbemycin Oxime + Spinosad 12
Imidacloprid + Moxidectin 10
Maropitant Citrate 9
Afoxolaner 9
Spinosad 7
Moxidectin 7
Fluralaner Spot-On Solution 7
Ivermectin + Pyrantel As Pamoate Salt 5
Emodepside + Praziquantel 4
Fluralaner Chew Tablets 4
Fluralaner 13.64% 12-Week Chew 4
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 3
Oclacitinib Maleate 3
Prednisone 3
Enrofloxacin 3
Selamectin;Sarolaner 3
Milbemycin Oxime + Praziquantel 3
Lotilaner 3
Bedinvetmab 3

Data Summary

Metric Value
Total reports referencing reaction 156
Reports with fatal outcome 8
Case-fatality rate (reported events) 510.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1836.

Throat irritation Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 156 adverse event reports that reference Throat irritation as a reaction term, including 8 reports with a death outcome — a 510.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1836, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Throat irritation appears most frequently in reports for Human (82 reports), Dog (56 reports), Cat (12 reports) — with Human dominating at 82 entries. Within those species, the breeds most often named alongside this reaction are Unknown (83), Domestic Shorthair (8), Retriever - Labrador (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Throat irritation are Selamectin (14 reports), Milbemycin Oxime + Spinosad (12 reports), Imidacloprid + Moxidectin (10 reports), Maropitant Citrate (9 reports), with Selamectin appearing alongside this reaction in 14 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial