Reaction profile

The FDA adverse-event record for pulmonary emphysema

45 FDA reports name pulmonary emphysema, a lower-volume reaction in the CVM extract (VeDDRA 845). Plate stamps and neighbourhood peers follow.

#1799 of 2,481
by report volume (all reactions)
45
reports citing this reaction
97.8%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pulmonary emphysema has 45 reports now versus 44 in that prior snapshot: 1 more (2.3%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pulmonary emphysema changes

FDA AER · VeDDRA plate

Code 845 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 45 reports
  • DEATH-HOT 97.8%
  • MID-PACK #1799/2481
  • PHOTO-FINISH Application site disc…
  • SPECIES-CATTLE Cattle · 26
  • DRUG-LEAD Tulathromycin · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site discharge NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Pulmonary emphysema

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site disc… · near45Buccal irritation · near45Chest tightness · near45Flaccid paralysis · near45Pulmonary emphysema · this r…45Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pulmonary emphysema

Pulmonary emphysema: high death-coded share in the FDA AER plate

Signature read: Pulmonary emphysema's 97.8% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 45 named reports in the openFDA extract. Death-coded share is upper-third: 44 of 45 reports (97.8% of named reports). Nearest volume peer: Application site discharge NOS (±0 reports). Lead species Cattle (26). Lead co-reported drug Tulathromycin (10).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 26
Dog 11
Cat 8

Breeds Most Affected

Domestic Shorthair 6
Cattle (other) 6
Aberdeen Angus 5
Cattle (unknown) 4
Mixed (Cattle) 3
Simmental 2
Shepherd Dog - Australian 2
Holstein-Friesian also known as Holstein 2
Jersey 2
Terrier - Boston 2

Associated Drugs

Tulathromycin 10
Trenbolone Acetate + Estradiol 8
Monensin Sodium 7
Ceftiofur 6
Florfenicol 6
Moxidectin 5
Lubabegron Fumarate 5
Trenbolone Acetate;Estradiol Benzoate 4
Spinosad 3
Milbemycin Oxime 3
Benadryl 3
Tylosin Phosphate 3
Danofloxacin 3
Dexamethasone 3
Eprinomectin 2
Clostr Perf*2/Clos Others*6 Kb 2
Ceftiofur Crystalline Free Acid 2
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 2
Robenacoxib 2
Buprenorphine 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pulmonary emphysema (#1799 of 2,481 by report volume); death-coded 97.8%. PlainBreed reaction plate · death-coded share stamp 97.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →