Reaction profile

The FDA adverse-event record for pulmonary emphysema

37 FDA adverse-event reports reference pulmonary emphysema (VeDDRA 845). See the species, breeds, and drugs most associated with it below.

37
reports citing this reaction
97.3%
death-coded share
Cattle
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
37
Total Reports
36
Deaths
97.3%
Death Rate

Species Most Affected

Cattle 20
Dog 11
Cat 6

Breeds Most Affected

Aberdeen Angus 5
Cattle (unknown) 4
Domestic Shorthair 4
Mixed (Cattle) 3
Simmental 2
Shepherd Dog - Australian 2
Holstein-Friesian also known as Holstein 2
Jersey 2
Cattle (other) 2
Terrier - Boston 2

Associated Drugs

Moxidectin 5
Monensin Sodium 5
Spinosad 3
Milbemycin Oxime 3
Benadryl 3
Eprinomectin 2
Clostr Perf*2/Clos Others*6 Kb 2
Ceftiofur Crystalline Free Acid 2
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 2
Tulathromycin 2
Robenacoxib 2
Fluralaner Spot-On Solution 2
Fluralaner 13.64% 12-Week Chew 2
Canine B Burgdorferi *2 Alu Kb 2
Isoflupredone 1
Carprofen 1
Doramectin 1
Zeniquin 1
Ivermectin 1
Flunixin Meglumine Injectable 1

Pulmonary emphysema Reaction Insights

37 reports name Pulmonary emphysema; 36 recorded a death outcome (97.3% of reported events, not a population-level mortality rate). VeDDRA code: 845.

By species: Cattle (20 reports), Dog (11 reports), Cat (6 reports). By breed: Aberdeen Angus (5), Cattle (unknown) (4), Domestic Shorthair (4).

Most co-reported drugs: Moxidectin (5 reports), Monensin Sodium (5 reports), Spinosad (3 reports), Milbemycin Oxime (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.