Reaction profile

The FDA adverse-event record for abnormal ecg

149 FDA adverse-event reports reference abnormal ecg (VeDDRA 2158). See the species, breeds, and drugs most associated with it below.

149
reports citing this reaction
40.9%
death-coded share
Dog
most-affected species
Robenacoxib
most-associated drug
Verify with FDA CVM →
149
Total Reports
61
Deaths
40.9%
Death Rate

Species Most Affected

Dog 87
Cat 49
Human 6
Lion 3
Tiger 2
Jaguar 1
Horse 1

Breeds Most Affected

Domestic (unspecified) 36
Unknown 13
Retriever - Labrador 9
Boxer (German Boxer) 8
Domestic Shorthair 8
Shih Tzu 5
Shepherd Dog - German 4
Dog (unknown) 4
Terrier - Yorkshire 4
Pinscher - Miniature 3

Associated Drugs

Robenacoxib 30
Dexmedetomidine Hydrochloride 14
Fluralaner Chew Tablets 11
Cefovecin 8
Carprofen 7
Maropitant Citrate 7
Moxidectin 7
Isoflurane 6
Ivermectin 5
Sevoflurane 5
Prednisone 5
Atropine 5
Oclacitinib Maleate 5
Milbemycin Oxime + Spinosad 5
Atipamezole Hydrochloride 5
Propofol 4
Butorphanol 4
Sarolaner 4
Selamectin 3
Spinosad 3

Abnormal ECG Reaction Insights

149 reports name Abnormal ECG; 61 recorded a death outcome (40.9% of reported events, not a population-level mortality rate). VeDDRA code: 2158.

By species: Dog (87 reports), Cat (49 reports), Human (6 reports). By breed: Domestic (unspecified) (36), Unknown (13), Retriever - Labrador (9).

Most co-reported drugs: Robenacoxib (30 reports), Dexmedetomidine Hydrochloride (14 reports), Fluralaner Chew Tablets (11 reports), Cefovecin (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.