Reaction profile

The FDA adverse-event record for mast cell tumour

394 FDA reports name mast cell tumour, a high-volume reaction in the CVM extract (VeDDRA 2729). Plate stamps and neighbourhood peers follow.

#736 of 2,481
by report volume (all reactions)
394
reports citing this reaction
11.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Mast cell tumour has 394 reports now versus 375 in that prior snapshot: 19 more (5.1%).

Report change
+19
Death-coded reports
+1
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Mast cell tumour changes

FDA AER · VeDDRA plate

Code 2729 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 394 reports
  • DEATH-ELEV 11.7%
  • MID-PACK #736/2481
  • PHOTO-FINISH Skin necrosis
  • SPECIES-DOG Dog · 374
  • DRUG-LEAD Oclacitinib Malea… · 192
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Skin necrosis (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Mast cell tumour

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Corneal disorder NOS · near396Hearing decreased · near396Lumbar pain · near396Skin necrosis · near395Mast cell tumour · this reac…394Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Mast cell tumour

What the FDA AER plate says about Mast cell tumour

Signature read: 394 reports place Mast cell tumour in the upper third of FDA AER volume (#736 of 2,481). Report volume is upper-third scale: 394 named reports in the openFDA extract. 46 of 394 reports were death-coded (11.7% of named reports, not a population mortality rate). Nearest volume peer: Skin necrosis (±1 reports). Lead species Dog (374). Lead co-reported drug Oclacitinib Maleate (192).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 374
Cat 20

Breeds Most Affected

Retriever - Labrador 54
Terrier - Bull - American Pit 52
Boxer (German Boxer) 26
Dog (unknown) 23
Crossbred Canine/dog 22
Bulldog - French 21
Retriever - Golden 19
Pug 15
Domestic Shorthair 15
Pit Bull 14

Associated Drugs

Oclacitinib Maleate 192
Tigilanol Tiglate 46
Prednisone 38
Gabapentin 37
Diphenhydramine 37
Anti-Il31 Mab Mcs Lot #1283563 31
Famotidine 31
Bedinvetmab 24
Moxidectin 21
Milbemycin Oxime + Praziquantel 19
Carprofen 18
Fluralaner 13.64% 12-Week Chew 14
Maropitant Citrate 14
Afoxolaner 12
Butorphanol Tartrate 12
Ilunocitinib 12
Cefpodoxime 11
Milbemycin Oxime + Spinosad 11
Butorphanol 11
Atipamezole Hydrochloride 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Mast cell tumour, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (394 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Mast cell tumour (#736 of 2,481 by report volume); death-coded 11.7%. PlainBreed reaction plate · report volume stamp 394 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →