Reaction profile

The FDA adverse-event record for injection site mucopurulent discharge

248 FDA adverse-event reports reference injection site mucopurulent discharge (VeDDRA 88). See the species, breeds, and drugs most associated with it below.

248
reports citing this reaction
8.5%
death-coded share
Dog
most-affected species
Tigilanol Tiglate
most-associated drug
Verify with FDA CVM →
248
Total Reports
21
Deaths
8.5%
Death Rate

Species Most Affected

Dog 224
Cat 11
Horse 7
Cattle 4
Alpaca 1
Human 1

Breeds Most Affected

Retriever - Labrador 20
Boxer (German Boxer) 16
Pit Bull 16
Crossbred Canine/dog 10
Chihuahua 10
Dog (unknown) 10
Bulldog - French 10
Retriever - Golden 9
Domestic Shorthair 8
Dachshund (unspecified) 6

Associated Drugs

Tigilanol Tiglate 100
Carprofen 54
Diphenhydramine 40
Prednisone 36
Gabapentin 36
Famotidine 31
Maropitant Citrate 29
Butorphanol 16
Moxidectin 16
Butorphanol Tartrate 16
Buprenorphine 13
Melarsomine Dihydrochloride 12
Dexmedetomidine 12
Propofol 12
Enrofloxacin 11
Dexmedetomidine Hydrochloride 11
Atipamezole 10
Cefovecin 8
Atipamezole Hydrochloride 8
Isoflurane 8

Injection site mucopurulent discharge Reaction Insights

248 reports name Injection site mucopurulent discharge; 21 recorded a death outcome (8.5% of reported events, not a population-level mortality rate). VeDDRA code: 88.

By species: Dog (224 reports), Cat (11 reports), Horse (7 reports). By breed: Retriever - Labrador (20), Boxer (German Boxer) (16), Pit Bull (16).

Most co-reported drugs: Tigilanol Tiglate (100 reports), Carprofen (54 reports), Diphenhydramine (40 reports), Prednisone (36 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.