Pulmonary disorder NOS

Verify with FDA CVM →

VeDDRA Code: 844

870 adverse event reports referencing this reaction

870
Total Reports
438
Deaths
5030.0%
Death Rate

Species Most Affected

Dog 629
Cat 140
Cattle 80
Horse 8
Pig 4
Human 2
Deer 2
Other Canids 1
Guinea Pig 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 102
Retriever - Labrador 74
Crossbred Canine/dog 47
Cattle (other) 31
Chihuahua 27
Beagle 21
Shepherd Dog - German 20
Dachshund (unspecified) 19
Holstein-Friesian also known as Holstein 19
Bulldog 19

Associated Drugs

Milbemycin Oxime + Spinosad 101
Spinosad 53
Maropitant Citrate 51
Carprofen 46
Ivermectin + Pyrantel As Pamoate Salt 45
Prednisone 43
Oclacitinib Maleate 38
Melarsomine Dihydrochloride 38
Cefovecin 33
Furosemide 30
Moxidectin 28
Melarsomine Dihydrochloride Injection 28
Doxycycline 28
Selamectin 27
Afoxolaner 26
Fluralaner Chew Tablets 26
Trilostane 25
Tulathromycin 25
Enrofloxacin 24
Buprenorphine 22

Data Summary

Metric Value
Total reports referencing reaction 870
Reports with fatal outcome 438
Case-fatality rate (reported events) 5030.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 844.

Pulmonary disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 870 adverse event reports that reference Pulmonary disorder NOS as a reaction term, including 438 reports with a death outcome — a 5030.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 844, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Pulmonary disorder NOS appears most frequently in reports for Dog (629 reports), Cat (140 reports), Cattle (80 reports) — with Dog dominating at 629 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (102), Retriever - Labrador (74), Crossbred Canine/dog (47). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Pulmonary disorder NOS are Milbemycin Oxime + Spinosad (101 reports), Spinosad (53 reports), Maropitant Citrate (51 reports), Carprofen (46 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 101 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial