Reaction profile

The FDA adverse-event record for pulmonary disorder nos

870 FDA adverse-event reports reference pulmonary disorder nos (VeDDRA 844). See the species, breeds, and drugs most associated with it below.

870
reports citing this reaction
50.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
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870
Total Reports
438
Deaths
50.3%
Death Rate

Species Most Affected

Dog 629
Cat 140
Cattle 80
Horse 8
Pig 4
Human 2
Deer 2
Other Canids 1
Guinea Pig 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 102
Retriever - Labrador 74
Crossbred Canine/dog 47
Cattle (other) 31
Chihuahua 27
Beagle 21
Shepherd Dog - German 20
Dachshund (unspecified) 19
Holstein-Friesian also known as Holstein 19
Bulldog 19

Associated Drugs

Milbemycin Oxime + Spinosad 101
Spinosad 53
Maropitant Citrate 51
Carprofen 46
Ivermectin + Pyrantel As Pamoate Salt 45
Prednisone 43
Oclacitinib Maleate 38
Melarsomine Dihydrochloride 38
Cefovecin 33
Furosemide 30
Moxidectin 28
Melarsomine Dihydrochloride Injection 28
Doxycycline 28
Selamectin 27
Afoxolaner 26
Fluralaner Chew Tablets 26
Trilostane 25
Tulathromycin 25
Enrofloxacin 24
Buprenorphine 22

Pulmonary disorder NOS Reaction Insights

870 reports name Pulmonary disorder NOS; 438 recorded a death outcome (50.3% of reported events, not a population-level mortality rate). VeDDRA code: 844.

By species: Dog (629 reports), Cat (140 reports), Cattle (80 reports). By breed: Domestic Shorthair (102), Retriever - Labrador (74), Crossbred Canine/dog (47).

Most co-reported drugs: Milbemycin Oxime + Spinosad (101 reports), Spinosad (53 reports), Maropitant Citrate (51 reports), Carprofen (46 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.