Reaction profile

The FDA adverse-event record for difficulty chewing

102 FDA adverse-event reports reference difficulty chewing (VeDDRA 2450). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1383 of 2,481
by report volume (all reactions)
102
reports citing this reaction
6.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Difficulty chewing has 102 reports now versus 100 in that prior snapshot: 2 more (2.0%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Difficulty chewing changes

FDA AER · VeDDRA plate

Code 2450 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 102 reports
  • DEATH-PAR 6.9%
  • MID-PACK #1383/2481
  • PHOTO-FINISH Agglutination test, p…
  • SPECIES-DOG Dog · 68
  • DRUG-LEAD Florfenicol + Mom… · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Agglutination test, positive (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Difficulty chewing

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Agglutination test, p… · near102Difficulty chewing · this re…102Facial rash (For urti… · near102Injection site sarcoma · near102PR-BRAIN, LESION(S) · near102Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Difficulty chewing

Difficulty chewing: low death-coded share in the FDA AER plate

Signature read: Difficulty chewing's 6.9% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 7 of 102 reports (6.9% of named reports). Nearest volume peer: Agglutination test, positive (±0 reports). Lead species Dog (68). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (15).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 68
Cat 25
Horse 8
Mule 1

Breeds Most Affected

Domestic Shorthair 17
Retriever - Labrador 9
Chihuahua 4
Crossbred Canine/dog 4
Collie - Border 4
Retriever - Golden 4
Pit Bull 3
Domestic Longhair 3
Terrier (unspecified) 2
Terrier - Boston 2

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 15
Maropitant Citrate 12
Gabapentin 9
Prednisone 8
Trilostane 8
Mirtazapine 7
Butorphanol 7
Ivermectin + Pyrantel As Pamoate Salt 6
Oclacitinib Maleate 5
Afoxolaner 5
Milbemycin Oxime + Praziquantel 5
Carprofen 5
Ketamine 5
Marbofloxacin 4
Anti-Il31 Mab Mcs Lot #1283563 4
Ivermectin + Praziquantel 4
Cyclosporine 4
Doxycycline 4
Dexmedetomidine 4
Buprenorphine 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Difficulty chewing, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (6.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Difficulty chewing (#1383 of 2,481 by report volume); death-coded 6.9%. PlainBreed reaction plate · death-coded share stamp 6.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →