Reaction profile

The FDA adverse-event record for lack of efficacy (protozoa) - coccidia

3,988 FDA adverse-event reports reference lack of efficacy (protozoa) - coccidia (VeDDRA 2803). See the species, breeds, and drugs most associated with it below.

3,988
reports citing this reaction
5.9%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
3,988
Total Reports
237
Deaths
5.9%
Death Rate

Species Most Affected

Dog 3,368
Cattle 385
Chicken 136
Cat 48
Turkey 19
Goat 14
Sheep 9
Other Birds 4
Rabbit 1
Bison 1

Breeds Most Affected

Retriever - Labrador 598
Retriever - Golden 321
Crossbred Canine/dog 273
Beagle 207
Shepherd Dog - German 142
Holstein-Friesian also known as Holstein 140
Chicken (unknown) 96
Shih Tzu 92
Shepherd Dog - Australian 73
Schnauzer - Miniature 68

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 1,602
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 199
Monensin Sodium 196
Milbemycin Oxime, Lufenuron 176
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 167
Milbemycin Oxime + Spinosad 162
Milbemycin Oxime + Praziquantel 151
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 138
Pyrantel Pamoate;Sarolaner 105
Lufenuron + Milbemycin Oxime 88
Sulfadimethoxine 78
Ivermectin, Pyrantel 72
Moxidectin 69
Milbemycin 59
Narasin + Nicarbazin 53
Monensin 50
Lasalocid Sodium 50
Narasin 48
Milbemycin Oxime 40
Decoquinate 38

Lack of efficacy (protozoa) - Coccidia Reaction Insights

3,988 reports name Lack of efficacy (protozoa) - Coccidia; 237 recorded a death outcome (5.9% of reported events, not a population-level mortality rate). VeDDRA code: 2803.

By species: Dog (3,368 reports), Cattle (385 reports), Chicken (136 reports). By breed: Retriever - Labrador (598), Retriever - Golden (321), Crossbred Canine/dog (273).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (1,602 reports), Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg (199 reports), Monensin Sodium (196 reports), Milbemycin Oxime, Lufenuron (176 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.