Reaction profile

The FDA adverse-event record for confusion

2,156 FDA adverse-event reports reference confusion (VeDDRA 659). See the species, breeds, and drugs most associated with it below.

2,156
reports citing this reaction
14.6%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
2,156
Total Reports
314
Deaths
14.6%
Death Rate

Species Most Affected

Dog 1,860
Cat 278
Horse 13
Cattle 4
Unknown 1

Breeds Most Affected

Crossbred Canine/dog 231
Retriever - Labrador 189
Domestic Shorthair 112
Domestic (unspecified) 85
Chihuahua 82
Terrier - Yorkshire 68
Retriever - Golden 66
Dog (unknown) 63
Shepherd Dog - German 58
Boxer (German Boxer) 49

Associated Drugs

Bedinvetmab 233
Milbemycin Oxime + Spinosad 215
Spinosad 162
Carprofen 143
Afoxolaner 124
Pyrantel Pamoate;Sarolaner 99
Maropitant Citrate 71
Fluralaner 13.64% 12-Week Chew 71
Gabapentin 68
Oclacitinib Maleate 59
Ivermectin + Pyrantel As Pamoate Salt 59
Trilostane 58
Sarolaner 52
Ivermectin 50
Meloxicam 48
Selamectin 44
Buprenorphine 42
Fluralaner Chew Tablets 39
Prednisone 31
Nitenpyram 30

Confusion Reaction Insights

2,156 reports name Confusion; 314 recorded a death outcome (14.6% of reported events, not a population-level mortality rate). VeDDRA code: 659.

By species: Dog (1,860 reports), Cat (278 reports), Horse (13 reports). By breed: Crossbred Canine/dog (231), Retriever - Labrador (189), Domestic Shorthair (112).

Most co-reported drugs: Bedinvetmab (233 reports), Milbemycin Oxime + Spinosad (215 reports), Spinosad (162 reports), Carprofen (143 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.