Reaction profile

The FDA adverse-event record for intestinal thickening

31 FDA reports name intestinal thickening, a lower-volume reaction in the CVM extract (VeDDRA 3159). Plate stamps and neighbourhood peers follow.

#1976 of 2,481
by report volume (all reactions)
31
reports citing this reaction
19.4%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Intestinal thickening has 31 reports now versus 13 in that prior snapshot: 18 more (138.5%).

Report change
+18
Death-coded reports
+1
Death-coded share
−19.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Intestinal thickening changes

FDA AER · VeDDRA plate

Code 3159 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 31 reports
  • DEATH-ELEV 19.4%
  • LOWER-Q #1976/2481
  • PHOTO-FINISH ABNORMAL TEST RESULT,…
  • SPECIES-DOG Dog · 17
  • DRUG-LEAD Maropitant Citrate · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Intestinal thickening

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL TEST RESULT,… · near31ALBUMIN HIGH, URINE · near31BILE ACIDS ABNORMAL,… · near31Clonic seizure · near31Intestinal thickening · this…31Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Intestinal thickening

What the FDA AER plate says about Intestinal thickening

Signature read: 31 reports place Intestinal thickening in the lower third of FDA AER volume (#1976 of 2,481). Report volume is lower-third scale: 31 named reports in the openFDA extract. 6 of 31 reports were death-coded (19.4% of named reports, not a population mortality rate). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Dog (17). Lead co-reported drug Maropitant Citrate (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 17
Cat 12
Horse 2

Breeds Most Affected

Domestic Shorthair 5
Terrier - Boston 3
Quarter Horse 2
Domestic Mediumhair 2
Chihuahua 2
Domestic Longhair 2
Spitz - German Pomeranian 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Hound - Basset 1
Pointing Dog - German Wire-haired 1

Associated Drugs

Maropitant Citrate 8
Bexagliflozin 5
Bedinvetmab 5
Gabapentin 4
Moxidectin 3
Capromorelin 3
Mirtazapine 3
Ondansetron 3
Trilostane 3
Frunevetmab 3
Metronidazole 3
Fluralaner Powder For Inj Susp 2
Omeprazole 2
Lotilaner 2
Fluids 2
Sucralfate 2
Famotidine 2
Velagliflozin Proline Monohydrate 2
Glucosamine/Chondroitin 2
Grapiprant 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Intestinal thickening (#1976 of 2,481 by report volume); death-coded 19.4%. PlainBreed reaction plate · report volume stamp 31 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →