Reaction profile

The FDA adverse-event record for increased culls

13 FDA adverse-event reports reference increased culls (VeDDRA 2513). See the species, breeds, and drugs most associated with it below.

13
reports citing this reaction
100.0%
death-coded share
Cattle
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
13
Total Reports
13
Deaths
100.0%
Death Rate

Species Most Affected

Cattle 10
Turkey 2
Dog 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 4
Turkey (unknown) 2
Cattle (other) 2
Mixed (Cattle) 1
Limousin 1
Jersey 1
Dog (unknown) 1
Cattle (unknown) 1

Associated Drugs

Monensin Sodium 5
Ceftiofur Hydrochloride 3
Dinoprost Tromethamine 2
Estradiol Benzoate; Testosterone Propionate 1
Estradiol Benzoate; Trenbolone Acetate 1
Melengestrol Acetate 1
Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost 1
Sometribove 1
Trenbolone Acetate;Estradiol Benzoate 1
Tulathromycin 1
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 1
Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 1
Febantel + Praziquantel + Pyrantel 1
E. Coli Strain J5, Lot #072692 1
Bismuth Subnitrate 1

Increased culls Reaction Insights

13 reports name Increased culls; 13 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). VeDDRA code: 2513.

By species: Cattle (10 reports), Turkey (2 reports), Dog (1 reports). By breed: Holstein-Friesian also known as Holstein (4), Turkey (unknown) (2), Cattle (other) (2).

Most co-reported drugs: Monensin Sodium (5 reports), Ceftiofur Hydrochloride (3 reports), Dinoprost Tromethamine (2 reports), Estradiol Benzoate; Testosterone Propionate (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.