Increased culls

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VeDDRA Code: 2513

13 adverse event reports referencing this reaction

13
Total Reports
13
Deaths
10000.0%
Death Rate

Species Most Affected

Cattle 10
Turkey 2
Dog 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 4
Turkey (unknown) 2
Cattle (other) 2
Mixed (Cattle) 1
Limousin 1
Jersey 1
Dog (unknown) 1
Cattle (unknown) 1

Associated Drugs

Monensin Sodium 5
Ceftiofur Hydrochloride 3
Dinoprost Tromethamine 2
Estradiol Benzoate; Testosterone Propionate 1
Estradiol Benzoate; Trenbolone Acetate 1
Melengestrol Acetate 1
Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost 1
Sometribove 1
Trenbolone Acetate;Estradiol Benzoate 1
Tulathromycin 1
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 1
Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 1
Febantel + Praziquantel + Pyrantel 1
E. Coli Strain J5, Lot #072692 1
Bismuth Subnitrate 1

Data Summary

Metric Value
Total reports referencing reaction 13
Reports with fatal outcome 13
Case-fatality rate (reported events) 10000.0%
Species observed 3
Breeds observed 8
Drugs associated with reaction 15

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2513.

Increased culls Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 13 adverse event reports that reference Increased culls as a reaction term, including 13 reports with a death outcome — a 10000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2513, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Increased culls appears most frequently in reports for Cattle (10 reports), Turkey (2 reports), Dog (1 reports) — with Cattle dominating at 10 entries. Within those species, the breeds most often named alongside this reaction are Holstein-Friesian also known as Holstein (4), Turkey (unknown) (2), Cattle (other) (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Increased culls are Monensin Sodium (5 reports), Ceftiofur Hydrochloride (3 reports), Dinoprost Tromethamine (2 reports), Estradiol Benzoate; Testosterone Propionate (1 reports), with Monensin Sodium appearing alongside this reaction in 5 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial