Reaction profile

The FDA adverse-event record for increased sensitivity to light

79 FDA adverse-event reports reference increased sensitivity to light (VeDDRA 1695). See the species, breeds, and drugs most associated with it below.

79
reports citing this reaction
1.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
79
Total Reports
1
Deaths
1.3%
Death Rate

Species Most Affected

Dog 67
Cat 9
Human 2
Horse 1

Breeds Most Affected

Chihuahua 10
Retriever - Golden 6
Beagle 5
Boxer (German Boxer) 5
Domestic Shorthair 5
Dachshund (unspecified) 4
Shih Tzu 3
Domestic Longhair 3
Terrier - Yorkshire 3
Terrier - West Highland White 2

Associated Drugs

Milbemycin Oxime + Spinosad 19
Sarolaner 11
Pyrantel Pamoate;Sarolaner 7
Maropitant Citrate 6
Bedinvetmab 6
Afoxolaner 5
Cyclosporine (Ophthalmic) 5
Pilocarpine 4
Oclacitinib Maleate 3
Gabapentin 3
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 3
Fluralaner 13.64% 12-Week Chew 3
Fluid Therapy 3
Pain Meds (Unknown) 3
Bacitracin + Neomycin + Polymyxin B 3
Eye Ointment (Unknown) 3
Pilocarpine Ophthalmic 3
Nitenpyram 2
Imidacloprid + Moxidectin 2
Anti-Il31 Mab Mcs Lot #1283563 2

Increased sensitivity to light Reaction Insights

79 reports name Increased sensitivity to light; 1 recorded a death outcome (1.3% of reported events, not a population-level mortality rate). VeDDRA code: 1695.

By species: Dog (67 reports), Cat (9 reports), Human (2 reports). By breed: Chihuahua (10), Retriever - Golden (6), Beagle (5).

Most co-reported drugs: Milbemycin Oxime + Spinosad (19 reports), Sarolaner (11 reports), Pyrantel Pamoate;Sarolaner (7 reports), Maropitant Citrate (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.