Reaction profile

The FDA adverse-event record for tubes, leaking

3,317 FDA adverse-event reports reference tubes, leaking (VeDDRA 99029). See the species, breeds, and drugs most associated with it below.

3,317
reports citing this reaction
0.1%
death-coded share
Unknown
most-affected species
Selamectin
most-associated drug
Verify with FDA CVM →
3,317
Total Reports
2
Deaths
0.1%
Death Rate

Species Most Affected

Unknown 3,070
Human 213
Cat 19
Dog 14
Cattle 1

Breeds Most Affected

Unknown 3,283
Domestic (unspecified) 5
Cat (unknown) 4
Domestic Shorthair 4
Crossbred Canine/dog 2
Dog (unknown) 2
Domestic Longhair 2
Retriever - Labrador 1
Spitz - German Pomeranian 1
Spaniel - Cocker American 1

Associated Drugs

Selamectin 722
Fluralaner Spot-On Solution 556
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 439
Cyclosporin Ointment 373
Selamectin;Sarolaner 274
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 193
Milbemycin Oxime 111
Mirtazapine 103
Milbemycin Oxime Solution 86
Imidacloprid + Moxidectin 75
Fluralaner/Moxidectin Spot-On 57
Cyclosporine 40
Emodepside + Praziquantel 30
Omeprazole 21
Genta/Betamet/Clotrim Ear Oint 16
Cephapirin Benzathine 12
Ivermectin 11
Triamcinolone Acetonide 0.015% 10
Omeprazole 37% Oral Paste 10
Device: Syringe 10

Tubes, Leaking Reaction Insights

3,317 reports name Tubes, Leaking; 2 recorded a death outcome (0.1% of reported events, not a population-level mortality rate). VeDDRA code: 99029.

By species: Unknown (3,070 reports), Human (213 reports), Cat (19 reports). By breed: Unknown (3,283), Domestic (unspecified) (5), Cat (unknown) (4).

Most co-reported drugs: Selamectin (722 reports), Fluralaner Spot-On Solution (556 reports), Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate (439 reports), Cyclosporin Ointment (373 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.