Tubes, Leaking

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VeDDRA Code: 99029

3,317 adverse event reports referencing this reaction

3,317
Total Reports
2
Deaths
10.0%
Death Rate

Species Most Affected

Unknown 3,070
Human 213
Cat 19
Dog 14
Cattle 1

Breeds Most Affected

Unknown 3,283
Domestic (unspecified) 5
Cat (unknown) 4
Domestic Shorthair 4
Crossbred Canine/dog 2
Dog (unknown) 2
Domestic Longhair 2
Retriever - Labrador 1
Spitz - German Pomeranian 1
Spaniel - Cocker American 1

Associated Drugs

Selamectin 722
Fluralaner Spot-On Solution 556
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 439
Cyclosporin Ointment 373
Selamectin;Sarolaner 274
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 193
Milbemycin Oxime 111
Mirtazapine 103
Milbemycin Oxime Solution 86
Imidacloprid + Moxidectin 75
Fluralaner/Moxidectin Spot-On 57
Cyclosporine 40
Emodepside + Praziquantel 30
Omeprazole 21
Genta/Betamet/Clotrim Ear Oint 16
Cephapirin Benzathine 12
Ivermectin 11
Triamcinolone Acetonide 0.015% 10
Omeprazole 37% Oral Paste 10
Device: Syringe 10

Data Summary

Metric Value
Total reports referencing reaction 3,317
Reports with fatal outcome 2
Case-fatality rate (reported events) 10.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99029.

Tubes, Leaking Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 3,317 adverse event reports that reference Tubes, Leaking as a reaction term, including 2 reports with a death outcome — a 10.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99029, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Tubes, Leaking appears most frequently in reports for Unknown (3,070 reports), Human (213 reports), Cat (19 reports) — with Unknown dominating at 3,070 entries. Within those species, the breeds most often named alongside this reaction are Unknown (3,283), Domestic (unspecified) (5), Cat (unknown) (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Tubes, Leaking are Selamectin (722 reports), Fluralaner Spot-On Solution (556 reports), Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate (439 reports), Cyclosporin Ointment (373 reports), with Selamectin appearing alongside this reaction in 722 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial