Conjunctivitis

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VeDDRA Code: 469

825 adverse event reports referencing this reaction

825
Total Reports
77
Deaths
930.0%
Death Rate

Species Most Affected

Dog 633
Cat 149
Human 22
Cattle 13
Horse 6
Chicken 1
Unknown 1

Breeds Most Affected

Domestic Shorthair 80
Retriever - Labrador 70
Crossbred Canine/dog 32
Maltese 28
Unknown 26
Retriever - Golden 24
Chihuahua 21
Boxer (German Boxer) 19
Shih Tzu 19
Bulldog 18

Associated Drugs

Milbemycin Oxime + Spinosad 127
Oclacitinib Maleate 45
Maropitant Citrate 43
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 43
Afoxolaner 36
Spinosad 33
Milbemycin Oxime + Praziquantel 31
Carprofen 30
Fluralaner Chew Tablets 28
Moxidectin 27
Cyclosporine 26
Trilostane 25
Imidacloprid + Moxidectin 24
Prednisone 23
Selamectin 21
Enrofloxacin 21
Cyclosporine A 19
Recombinant Human Insulin 18
Cefovecin Sodium 16
Famotidine 16

Data Summary

Metric Value
Total reports referencing reaction 825
Reports with fatal outcome 77
Case-fatality rate (reported events) 930.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 469.

Conjunctivitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 825 adverse event reports that reference Conjunctivitis as a reaction term, including 77 reports with a death outcome — a 930.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 469, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Conjunctivitis appears most frequently in reports for Dog (633 reports), Cat (149 reports), Human (22 reports) — with Dog dominating at 633 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (80), Retriever - Labrador (70), Crossbred Canine/dog (32). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Conjunctivitis are Milbemycin Oxime + Spinosad (127 reports), Oclacitinib Maleate (45 reports), Maropitant Citrate (43 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (43 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 127 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial