Reaction profile

The FDA adverse-event record for partial blindness

225 FDA adverse-event reports reference partial blindness (VeDDRA 409). See the species, breeds, and drugs most associated with it below.

225
reports citing this reaction
13.3%
death-coded share
Dog
most-affected species
Ivermectin
most-associated drug
Verify with FDA CVM →
225
Total Reports
30
Deaths
13.3%
Death Rate

Species Most Affected

Dog 165
Cat 50
Cattle 8
Horse 1
Goat 1

Breeds Most Affected

Domestic Shorthair 23
Crossbred Canine/dog 18
Retriever - Labrador 11
Domestic (unspecified) 10
Dog (unknown) 9
Chihuahua 9
Shih Tzu 7
Terrier - Yorkshire 6
Spitz - German Pomeranian 6
Holstein-Friesian also known as Holstein 5

Associated Drugs

Ivermectin 23
Milbemycin Oxime + Spinosad 20
Spinosad 16
Enrofloxacin 12
Fluralaner Chew Tablets 10
Meloxicam 8
Carprofen 8
Trilostane 8
Orbifloxacin Oral Suspension 7
Afoxolaner 6
Milbemycin Oxime + Praziquantel 5
Fluralaner 13.64% 12-Week Chew 5
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 5
Bedinvetmab 5
Robenacoxib 4
Cefovecin 4
Phenobarbital 4
Insulin Injectable Vial 4
Ivermectin + Pyrantel As Pamoate Salt 4
Prednisone 4

Partial blindness Reaction Insights

225 reports name Partial blindness; 30 recorded a death outcome (13.3% of reported events, not a population-level mortality rate). VeDDRA code: 409.

By species: Dog (165 reports), Cat (50 reports), Cattle (8 reports). By breed: Domestic Shorthair (23), Crossbred Canine/dog (18), Retriever - Labrador (11).

Most co-reported drugs: Ivermectin (23 reports), Milbemycin Oxime + Spinosad (20 reports), Spinosad (16 reports), Enrofloxacin (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.