Reaction profile

The FDA adverse-event record for pr-heartworm disease

44 FDA adverse-event reports reference pr-heartworm disease (VeDDRA 99620). See the species, breeds, and drugs most associated with it below.

44
reports citing this reaction
100.0%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
44
Total Reports
44
Deaths
100.0%
Death Rate

Species Most Affected

Dog 38
Cat 5
Ferret 1

Breeds Most Affected

Crossbred Canine/dog 7
Retriever - Labrador 7
Chihuahua 3
Domestic (unspecified) 2
Hound - Basset 2
Pit Bull 2
Boxer (German Boxer) 2
Domestic Shorthair 2
Mixed (Dog) 1
Beagle 1

Associated Drugs

Moxidectin 9
Selamectin 5
Ivermectin, Pyrantel 5
Milbemycin Oxime + Spinosad 4
Melarsomine Dihydrochloride 3
Rabies Vaccine 3
Fluralaner Chew Tablets 3
Milbemycin, Lufenuron 2
Dexamethasone 2
Bordetella Vaccine 2
Metronidazole 2
Imidacloprid + Moxidectin 2
Maropitant Citrate 2
Firocoxib 1
Neomycin Sulfate, Nystatin, Thiostrepton, Triamcinolone Acetonide 1
Dexmedetomidine Hydrochloride 1
Toceranib Phosphate 1
Carprofen 1
Penicillin 1
Flunixin Meglumine 1

PR-HEARTWORM DISEASE Reaction Insights

44 reports name PR-HEARTWORM DISEASE; 44 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). VeDDRA code: 99620.

By species: Dog (38 reports), Cat (5 reports), Ferret (1 reports). By breed: Crossbred Canine/dog (7), Retriever - Labrador (7), Chihuahua (3).

Most co-reported drugs: Moxidectin (9 reports), Selamectin (5 reports), Ivermectin, Pyrantel (5 reports), Milbemycin Oxime + Spinosad (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.