Reaction profile

The FDA adverse-event record for pr-heartworm disease

44 FDA reports name pr-heartworm disease, a lower-volume reaction in the CVM extract (VeDDRA 99620). Plate stamps and neighbourhood peers follow.

#1808 of 2,481
by report volume (all reactions)
44
reports citing this reaction
100.0%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-HEARTWORM DISEASE has 44 reports now versus 44 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-HEARTWORM DISEASE changes

FDA AER · VeDDRA plate

Code 99620 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 44 reports
  • DEATH-HOT 100.0%
  • MID-PACK #1808/2481
  • PHOTO-FINISH Administration device…
  • SPECIES-DOG Dog · 38
  • DRUG-LEAD Moxidectin · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Administration device NOS, breakage (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-HEARTWORM DISEASE

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Administration device… · near44Diabetes insipidus · near44Eye stinging · near44Flaccid muscles · near44PR-HEARTWORM DISEASE · this …44Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-HEARTWORM DISEASE

PR-HEARTWORM DISEASE: high death-coded share in the FDA AER plate

Signature read: PR-HEARTWORM DISEASE's 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 44 named reports in the openFDA extract. Death-coded share is upper-third: 44 of 44 reports (100.0% of named reports). Nearest volume peer: Administration device NOS, breakage (±0 reports). Lead species Dog (38). Lead co-reported drug Moxidectin (9).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 38
Cat 5
Ferret 1

Breeds Most Affected

Crossbred Canine/dog 7
Retriever - Labrador 7
Chihuahua 3
Domestic (unspecified) 2
Hound - Basset 2
Pit Bull 2
Boxer (German Boxer) 2
Domestic Shorthair 2
Mixed (Dog) 1
Beagle 1

Associated Drugs

Moxidectin 9
Selamectin 5
Ivermectin, Pyrantel 5
Milbemycin Oxime + Spinosad 4
Melarsomine Dihydrochloride 3
Rabies Vaccine 3
Fluralaner Chew Tablets 3
Milbemycin, Lufenuron 2
Dexamethasone 2
Bordetella Vaccine 2
Imidacloprid + Moxidectin 2
Metronidazole 2
Maropitant Citrate 2
Neomycin Sulfate, Nystatin, Thiostrepton, Triamcinolone Acetonide 1
Firocoxib 1
Toceranib Phosphate 1
Dexmedetomidine Hydrochloride 1
Carprofen 1
Penicillin 1
Flunixin Meglumine 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-HEARTWORM DISEASE (#1808 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →