Reaction profile

The FDA adverse-event record for gum disorder nos

201 FDA adverse-event reports reference gum disorder nos (VeDDRA 1501). See the species, breeds, and drugs most associated with it below.

201
reports citing this reaction
18.4%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
201
Total Reports
37
Deaths
18.4%
Death Rate

Species Most Affected

Dog 158
Cat 33
Horse 9
Human 1

Breeds Most Affected

Domestic Shorthair 23
Crossbred Canine/dog 16
Retriever - Labrador 15
Shepherd Dog - German 11
Retriever - Golden 11
Pit Bull 7
Beagle 7
Boxer (German Boxer) 6
Terrier - Yorkshire 5
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 5

Associated Drugs

Milbemycin Oxime + Spinosad 22
Maropitant Citrate 12
Spinosad 11
Milbemycin Oxime + Praziquantel 11
Moxidectin 10
Cyclosporine 10
Robenacoxib 10
Buprenorphine 10
Oclacitinib Maleate 9
Bedinvetmab 9
Meloxicam 8
Cyclosporine A 8
Carprofen 8
Afoxolaner 7
Rabies Vaccine 7
Pyrantel Pamoate;Sarolaner 7
Fluid Therapy 7
Nitenpyram 6
Fluralaner 13.64% 12-Week Chew 6
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 6

Gum disorder NOS Reaction Insights

201 reports name Gum disorder NOS; 37 recorded a death outcome (18.4% of reported events, not a population-level mortality rate). VeDDRA code: 1501.

By species: Dog (158 reports), Cat (33 reports), Horse (9 reports). By breed: Domestic Shorthair (23), Crossbred Canine/dog (16), Retriever - Labrador (15).

Most co-reported drugs: Milbemycin Oxime + Spinosad (22 reports), Maropitant Citrate (12 reports), Spinosad (11 reports), Milbemycin Oxime + Praziquantel (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.