Reaction profile

The FDA adverse-event record for quadriplegia

46 FDA adverse-event reports reference quadriplegia (VeDDRA 694). See the species, breeds, and drugs most associated with it below.

46
reports citing this reaction
50.0%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
46
Total Reports
23
Deaths
50.0%
Death Rate

Species Most Affected

Dog 37
Cat 6
Turkey 1
Cattle 1
Quail 1

Breeds Most Affected

Crossbred Canine/dog 4
Domestic Shorthair 4
Retriever - Labrador 3
Dachshund (unspecified) 3
Shepherd Dog - German 3
Dalmatian 2
Chihuahua 2
Sheepdog (unspecified) 2
Terrier - Bull - American Pit 2
Turkey (unknown) 1

Associated Drugs

Carprofen 6
Spinosad 5
Bedinvetmab 5
Gabapentin 4
Fluid Therapy 3
Monensin 2
Deracoxib 2
Fluralaner Chew Tablets 2
Diphenhydramine 2
Sarolaner 2
Moxidectin 2
Ivermectin + Pyrantel As Pamoate Salt 2
Maropitant Citrate 2
Capromorelin Tartrate 2
Mirtazapine 2
Prescription Diet 2
Butorphanol Tartrate 1
Insulin 1
Doramectin 1
Cefovecin Sodium 1

Quadriplegia Reaction Insights

46 reports name Quadriplegia; 23 recorded a death outcome (50.0% of reported events, not a population-level mortality rate). VeDDRA code: 694.

By species: Dog (37 reports), Cat (6 reports), Turkey (1 reports). By breed: Crossbred Canine/dog (4), Domestic Shorthair (4), Retriever - Labrador (3).

Most co-reported drugs: Carprofen (6 reports), Spinosad (5 reports), Bedinvetmab (5 reports), Gabapentin (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.